Hydrocof-HC Interactions
There are 778 drugs known to interact with Hydrocof-HC (chlorpheniramine / hydrocodone / pseudoephedrine), along with 26 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 225 are major, 545 are moderate, and 8 are minor.
- View all 778 medications that may interact with Hydrocof-HC
- View Hydrocof-HC alcohol/food interactions (2)
- View Hydrocof-HC disease interactions (26)
Most frequently checked interactions
View interaction reports for Hydrocof-HC (chlorpheniramine / hydrocodone / pseudoephedrine) and the medicines listed below.
- acetaminophen / hydrocodone
- Acidophilus (lactobacillus acidophilus)
- Advair Diskus (fluticasone / salmeterol)
- Advair HFA (fluticasone / salmeterol)
- albuterol
- alendronate
- Aleve (naproxen)
- alprazolam
- amitriptyline
- amlodipine
- Artificial Tears (ocular lubricant ophthalmic)
- atorvastatin
- cyclobenzaprine
- Cymbalta (duloxetine)
- gabapentin
- hydrocodone
- lorazepam
- magnesium oxide
- Metoprolol Succinate ER (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- PreserVision (multivitamin with minerals)
- ranitidine
- Senna Plus (docusate/senna)
- Thera-Tabs (multivitamin)
- tizanidine
- topiramate
- tramadol
- trazodone
- Vitamin D3 (cholecalciferol)
- Zofran (ondansetron)
Hydrocof-HC alcohol/food interactions
There are 2 alcohol/food interactions with Hydrocof-HC (chlorpheniramine / hydrocodone / pseudoephedrine).
Hydrocof-HC disease interactions
There are 26 disease interactions with Hydrocof-HC (chlorpheniramine / hydrocodone / pseudoephedrine) which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- GI narrowing
- PKU
- BPH
- diabetes
- glaucoma
Report options
More about Hydrocof-HC (chlorpheniramine / hydrocodone / pseudoephedrine)
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.