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Tylenol Cold Head Congestion Severe (acetaminophen / guaifenesin / phenylephrine) Drug Interactions

A total of 453 drugs are known to interact with Tylenol Cold Head Congestion Severe (acetaminophen / guaifenesin / phenylephrine).

  • 81 major drug interactions
  • 333 moderate drug interactions
  • 39 minor drug interactions

Show all medications in the database that may interact with Tylenol Cold Head Congestion Severe (acetaminophen / guaifenesin / phenylephrine).

Check for interactions with Tylenol Cold Head Congestion Severe (acetaminophen / guaifenesin / phenylephrine)

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Common medications checked in combination with Tylenol Cold Head Congestion Severe (acetaminophen / guaifenesin / phenylephrine)

  • alprazolam (Xanax, Alprazolam Intensol, Xanax XR, Niravam)
  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Aspir-Low, Bayer Aspirin, Ecotrin Adult Low Strength, Ascriptin, Fasprin, Arthritis Pain, Low Dose ASA, Aspiritab, Bufferin, Durlaza, Aspirin Lite Coat, Aspirtab, Halfprin, Bayer Children's Aspirin, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Easprin, Aspergum, Buffered Aspirin, Ascriptin Enteric, Acuprin 81, Miniprin, Bayer Aspirin Regimen, St. Joseph 81 mg Chewable Aspirin, Empirin, Ecotrin Maximum Strength, St. Joseph Aspirin, Ecpirin, Bayer Women's Aspirin With Calcium, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Aspi-Cor, Bufferin Low Dose, Medi-Seltzer, Sloprin, ZORprin, Bayer Aspirin Extra Strength Plus, Buffex, Entercote, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Zero-Order Release, YSP Aspirin, Migralex, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Doryx (doxycycline)
  • doxycycline (Vibramycin, Oracea, Doxy 100, Doryx, Vibra-Tabs, Monodox, Adoxa, Acticlate, Targadox, Oraxyl, Alodox, Doxy-D, Morgidox, Adoxa Pak, Avidoxy, Uracil, Periostat, Doxy 200, Doryx MPC, Doxy-Caps, Adoxa TT, Adoxa CK, Ocudox, LymePak, Mondoxyne NL, NicAzel Doxy, Doxy-Lemmon)
  • Flonase (fluticasone nasal)
  • Flonase Sensimist (fluticasone nasal)
  • fluticasone nasal (Flonase, Flonase Sensimist, Flonase Allergy Relief, Veramyst, Xhance, Ticanase)
  • hydrocodone (Hysingla ER, Zohydro ER, Vantrela ER)
  • ibuprofen (Advil, Motrin, IBU, Proprinal, Advil Liqui-Gels, Motrin IB, IBU-200, Nuprin, Children's Motrin, Motrin Migraine Pain, Advil Migraine, Caldolor, Ibuprofen PMR, Advil Children's, Addaprin, NeoProfen, Advil Infant's Concentrated Drops, A-G Profen, Motrin Childrens, Childrens Ibuprofen Berry, Ibu-6, Ibu-8, Motrin Infant Drops, Ibu-Tab, Rufen, Genpril, Haltran, Menadol, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
  • loratadine (Claritin, Alavert, Allergy Relief Tablets, Claritin 24 Hour Allergy, Claritin Reditabs, Loratadine Reditab, Wal-itin, Help I Have Allergies, Children's Claritin Allergy, Allergy Relief 24 Hour, Children's Allergy Relief 24 Hour, Vicks QlearQuil All Day & All Night 24 Hour Allergy Relief, ohm Allergy Relief, Clear-Atadine, Claritin Hives Relief, Dimetapp Children's ND Non-Drowsy Allergy, Clear-Atadine Children's, Bactimicina Allergy, Tavist ND)
  • Mucinex Fast-Max Severe Congestion & Cough (dextromethorphan / guaifenesin / phenylephrine)
  • oxycodone (OxyContin, Roxicodone, Xtampza ER, OxyIR, Oxaydo, Percolone, Oxyfast, Dazidox, RoxyBond, Oxecta, Oxydose, M-Oxy, ETH-Oxydose, Endocodone, Roxicodone Intensol)
  • Plavix (clopidogrel)
  • Protonix (pantoprazole)
  • ranitidine (Zantac, Zantac 150, Zantac 75, Zantac 300, Deprizine, Zantac Injection, Acid Reducer, Zantac 25 mg EFFERdose, Berkley and Jensen Acid Reducer Maximum Strength, Zantac GELdose, Zantac 300 GELdose, Zantac EFFERdose, Acid Reducer Non-Prescription Strength, Acid Relief, Sunmark Acid Reducer Maximum Strength, Zantac 150 EFFERdose, Acid Control 75, Taladine, Careone Acid Reducer, Equaline Heartburn Relief, Acid Control 150)
  • simvastatin (Zocor, FloLipid)
  • terazosin (Hytrin)
  • trazodone (Desyrel, Oleptro, Desyrel Dividose)
  • Vicks Nyquil D Cold and Flu Nighttime Relief (acetaminophen / dextromethorphan / doxylamine / pseudoephedrine)
  • ZzzQuil (diphenhydramine)

Tylenol Cold Head Congestion Severe (acetaminophen / guaifenesin / phenylephrine) alcohol/food interactions

There is 1 alcohol/food interaction with Tylenol Cold Head Congestion Severe (acetaminophen / guaifenesin / phenylephrine)

Tylenol Cold Head Congestion Severe (acetaminophen / guaifenesin / phenylephrine) disease interactions

There are 7 disease interactions with Tylenol Cold Head Congestion Severe (acetaminophen / guaifenesin / phenylephrine) which include:

More about Tylenol Cold Head Congestion Severe (acetaminophen / guaifenesin / phenylephrine)

Related treatment guides

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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