Alka-Seltzer Plus Cold (acetaminophen / chlorpheniramine / phenylephrine) Drug Interactions
A total of 528 drugs are known to interact with Alka-Seltzer Plus Cold (acetaminophen / chlorpheniramine / phenylephrine).
- 41 major drug interactions
- 473 moderate drug interactions
- 14 minor drug interactions
Check for interactions
Most frequently checked interactions
View interaction reports for Alka-Seltzer Plus Cold (acetaminophen / chlorpheniramine / phenylephrine) and the medicines listed below.
- acetaminophen
- amlodipine
- aspirin
- atorvastatin
- Benadryl (diphenhydramine)
- doxycycline
- gabapentin
- ibuprofen
- levothyroxine
- lisinopril
- melatonin
- meloxicam
- metformin
- Mucinex (guaifenesin)
- omeprazole
- prednisone
- tramadol
- Tylenol (acetaminophen)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
Alka-Seltzer Plus Cold (acetaminophen / chlorpheniramine / phenylephrine) alcohol/food interactions
There is 1 alcohol/food interaction with Alka-Seltzer Plus Cold (acetaminophen / chlorpheniramine / phenylephrine)
Alka-Seltzer Plus Cold (acetaminophen / chlorpheniramine / phenylephrine) disease interactions
There are 11 disease interactions with Alka-Seltzer Plus Cold (acetaminophen / chlorpheniramine / phenylephrine) which include:
- alcoholism
- liver disease
- cardiovascular disease
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- BPH
- diabetes
- glaucoma
More about Alka-Seltzer Plus Cold (acetaminophen / chlorpheniramine / phenylephrine)
- Side Effects
- Dosage Information
- Drug Images
- En Español
- 8 Reviews
- Drug class: upper respiratory combinations
- FDA Alerts (3)
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
