Acetaminophen/caffeine/guaifenesin/phenylephrine Drug Interactions
Currently displaying a list of 378 drugs known to interact with acetaminophen / caffeine / guaifenesin / phenylephrine.
- 38 major drug interactions
- 310 moderate drug interactions
- 30 minor drug interactions
Medications known to interact with acetaminophen/caffeine/guaifenesin/phenylephrine
Note: Showing generic names only.
A
- abametapir topical
- acarbose
- acebutolol
- acetohexamide
- adenosine
- albiglutide
- albuterol
- alogliptin
- alosetron
- aminophylline
- amitriptyline
- amobarbital
- amoxapine
- amphetamine
- anagrelide
- anisindione
- apalutamide
- apraclonidine ophthalmic
- arformoterol
- armodafinil
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- aspirin
- atazanavir
- atenolol
- atezolizumab
- atomoxetine
- atropine
- atropine ophthalmic
- avelumab
B
- bedaquiline
- belladonna
- bendamustine
- benoxinate ophthalmic
- benzocaine topical
- benzphetamine
- benztropine
- betaxolol
- betaxolol ophthalmic
- bexagliflozin
- biperiden
- bisoprolol
- bitolterol
- black cohosh
- brentuximab
- bupivacaine
- bupivacaine liposome
- bupropion
- busulfan
- butabarbital
- butalbital
C
- calaspargase pegol
- canagliflozin
- cannabidiol
- capmatinib
- carbamazepine
- carteolol
- carteolol ophthalmic
- carvedilol
- cemiplimab
- ceritinib
- charcoal
- chloroprocaine
- chloroprocaine ophthalmic
- chlorpropamide
- cholestyramine
- cimetidine
- ciprofloxacin
- clidinium
- clofarabine
- clomipramine
- clozapine
- cocaine nasal
- cocaine topical
- colchicine
- cosibelimab
- cyclopentolate ophthalmic
- cycloserine
D
- daclizumab
- dapagliflozin
- darifenacin
- deferasirox
- deserpidine
- desipramine
- desvenlafaxine
- dexmethylphenidate
- dextroamphetamine
- diazepam
- dibucaine topical
- dicumarol
- dicyclomine
- diethylpropion
- diflunisal
- digitoxin
- digoxin
- dihydroergotamine
- dipyridamole
- disulfiram
- dobutamine
- dopamine
- dostarlimab
- doxapram
- doxepin
- droxidopa
- dulaglutide
- duloxetine
- durvalumab
E
- echinacea
- efavirenz
- empagliflozin
- encorafenib
- enoxacin
- ephedrine
- epinephrine
- epirubicin
- epoprostenol
- ergonovine
- ergotamine
- ertugliflozin
- esketamine
- esmolol
- ethanol
- ethinyl estradiol
- ethotoin
- etidocaine
- etranacogene dezaparvovec
- exenatide
F
- fenfluramine
- fenofibrate
- fenoldopam
- fexinidazole
- fezolinetant
- fidanacogene elaparvovec
- flavoxate
- fluvoxamine
- formoterol
- fosphenytoin
- furazolidone
G
- givosiran
- glimepiride
- glipizide
- glyburide
- glycerol phenylbutyrate
- glycopyrrolate
- grepafloxacin
- guanadrel
- guanethidine
H
I
- idelalisib
- iloprost
- imatinib
- imipramine
- indacaterol
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- interferon beta-1a
- interferon beta-1b
- iobenguane I 123
- iobenguane I 131
- ipilimumab
- isocarboxazid
- isoetharine
- isoniazid
- isoproterenol
K
L
- labetalol
- landiolol
- leflunomide
- leniolisib
- levalbuterol
- levobetaxolol ophthalmic
- levobunolol ophthalmic
- levobupivacaine
- levodopa
- levoketoconazole
- levomilnacipran
- levothyroxine
- lidocaine
- lidocaine ophthalmic
- lidocaine otic
- lidocaine topical
- linagliptin
- linezolid
- liothyronine
- liraglutide
- lisdexamfetamine
- lithium
- lixisenatide
- lomitapide
- lorlatinib
M
- ma huang
- mavorixafor
- mazindol
- mecamylamine
- melatonin
- mepenzolate
- mephentermine
- mephenytoin
- mephobarbital
- mepivacaine
- metaproterenol
- metaraminol
- metformin
- methamphetamine
- methohexital
- methotrexate
- methoxamine
- methscopolamine
- methyldopa
- methylene blue
- methylergonovine
- methylphenidate
- methysergide maleate
- metipranolol ophthalmic
- metoclopramide
- metoprolol
- mibefradil
- midodrine
- miglitol
- milnacipran
- mipomersen
- modafinil
N
- nadolol
- nalidixic acid
- naltrexone
- nateglinide
- nebivolol
- nicotine
- niraparib
- nivolumab
- norepinephrine
- norfloxacin
- nortriptyline
O
- obeticholic acid
- olaparib
- olodaterol
- olutasidenib
- omaveloxolone
- orphenadrine
- osilodrostat
- osimertinib
- ospemifene
- oxazepam
- oxybutynin
- oxytocin
- ozanimod
P
- pacritinib
- pegaspargase
- peginterferon beta-1a
- pembrolizumab
- penbutolol
- penpulimab
- pentobarbital
- pexidartinib
- phendimetrazine
- phenelzine
- phenobarbital
- phentermine
- phenylpropanolamine
- phenytoin
- pimozide
- pindolol
- pioglitazone
- pirbuterol
- pirtobrutinib
- pitolisant
- pneumococcal 13-valent vaccine
- pneumococcal 15-valent conjugate vaccine
- pneumococcal 20-valent conjugate vaccine
- pneumococcal 21-valent conjugate vaccine
- pneumococcal 7-valent vaccine
- pralsetinib
- pramlintide
- pramoxine topical
- primidone
- probenecid
- procaine
- procarbazine
- procyclidine
- propantheline
- proparacaine ophthalmic
- propranolol
- protriptyline
- pseudoephedrine
R
- racepinephrine
- ramelteon
- ranitidine
- ranitidine bismuth citrate
- rasagiline
- rauwolfia serpentina
- regadenoson
- remdesivir
- repaglinide
- reserpine
- retifanlimab
- rifampin
- riluzole
- ritlecitinib
- ritodrine
- ropinirole
- ropivacaine
- rosiglitazone
- rucaparib
S
- safinamide
- salmeterol
- saxagliptin
- scopolamine
- scopolamine ophthalmic
- secobarbital
- selegiline
- selexipag
- semaglutide
- sibutramine
- sitagliptin
- sodium salicylate
- solifenacin
- solriamfetol
- sotagliflozin
- sotalol
- stiripentol
- sulfinpyrazone
T
- tafamidis
- tapentadol
- terbinafine
- terbutaline
- teriflunomide
- tetracaine
- tetracaine ophthalmic
- tetracaine topical
- theophylline
- thiabendazole
- thioguanine
- thiopental
- thyroid desiccated
- timolol
- timolol ophthalmic
- tirzepatide
- tislelizumab
- tizanidine
- tolazamide
- tolbutamide
- tolterodine
- topotecan
- toripalimab
- trabectedin
- tranylcypromine
- tremelimumab
- treprostinil
- trihexyphenidyl
- trimipramine
- troglitazone
- tropicamide ophthalmic
- trospium
- trovafloxacin
V
W
Z
Acetaminophen/caffeine/guaifenesin/phenylephrine alcohol/food interactions
There are 6 alcohol/food interactions with acetaminophen / caffeine / guaifenesin / phenylephrine.
Acetaminophen/caffeine/guaifenesin/phenylephrine disease interactions
There are 16 disease interactions with acetaminophen / caffeine / guaifenesin / phenylephrine which include:
- alcoholism
- liver disease
- cardiac disease
- hypertension
- psychiatric disorders
- PUD
- cardiovascular disease
- PKU
- cardiotoxicity
- liver disease
- renal dysfunction
- seizure disorders
- GERD
- BPH
- diabetes
- glaucoma
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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