Acetaminophen/caffeine/guaifenesin/phenylephrine Interactions
There are 378 drugs known to interact with acetaminophen/caffeine/guaifenesin/phenylephrine, along with 16 disease interactions, and 6 alcohol/food interactions. Of the total drug interactions, 38 are major, 310 are moderate, and 30 are minor.
- View all 378 medications that may interact with acetaminophen/caffeine/guaifenesin/phenylephrine
- View acetaminophen/caffeine/guaifenesin/phenylephrine alcohol/food interactions (6)
- View acetaminophen/caffeine/guaifenesin/phenylephrine disease interactions (16)
Most frequently checked interactions
View interaction reports for acetaminophen / caffeine / guaifenesin / phenylephrine and the medicines listed below.
- Abilify (aripiprazole)
- Abilify (aripiprazole)
- Allegra (fexofenadine)
- Allegra (fexofenadine)
- Ambien (zolpidem)
- Ambien (zolpidem)
- Ambien CR (zolpidem)
- Ambien CR (zolpidem)
- Aspirin Low Strength (aspirin)
- Aspirin Low Strength (aspirin)
- Calcium, Magnesium and Zinc (multivitamin with minerals)
- Calcium, Magnesium and Zinc (multivitamin with minerals)
- Kapidex (dexlansoprazole)
- Kapidex (dexlansoprazole)
- Lipitor (atorvastatin)
- Lipitor (atorvastatin)
- Lovaza (omega-3 polyunsaturated fatty acids)
- Lovaza (omega-3 polyunsaturated fatty acids)
- Minipress (prazosin)
- Minipress (prazosin)
- Motrin (ibuprofen)
- Motrin (ibuprofen)
- Nasonex (mometasone nasal)
- Nasonex (mometasone nasal)
- Niaspan (niacin)
- Niaspan (niacin)
- Prilosec (omeprazole)
- Prilosec (omeprazole)
- Ritalin (methylphenidate)
- Ritalin (methylphenidate)
Acetaminophen/caffeine/guaifenesin/phenylephrine alcohol/food interactions
There are 6 alcohol/food interactions with acetaminophen / caffeine / guaifenesin / phenylephrine.
Acetaminophen/caffeine/guaifenesin/phenylephrine disease interactions
There are 16 disease interactions with acetaminophen / caffeine / guaifenesin / phenylephrine which include:
- alcoholism
- liver disease
- cardiac disease
- hypertension
- psychiatric disorders
- PUD
- cardiovascular disease
- PKU
- cardiotoxicity
- liver disease
- renal dysfunction
- seizure disorders
- GERD
- BPH
- diabetes
- glaucoma
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Advil Allergy Sinus
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Advil Children's Allergy Sinus
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Advil Cold and Sinus Liqui-Gels
Advil Cold and Sinus Liqui-Gels is used for sinus symptoms
Advil Sinus Congestion & Pain
Advil Sinus Congestion & Pain is used for cold symptoms, nasal congestion, sinus symptoms
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.