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What are Sulfonamides

Sulphonamides (sulfa drugs) are one of a group of drugs derived from sulphanilamide that prevents the growth of bacteria.

Sulphonamides compete with p-aminobenzoic acid (PABA) for the enzyme dihydropteroate synthetase, which is important in the formation of folic acid that is required by the bacteria. Folic acid is required for the synthesis of precursors of DNA and RNA both in bacteria and in mammals. Mammals obtain their folic acid in their diet but bacteria need to synthesize it. Sulphonamides inhibit the growth of bacteria but do not kill them i.e. their action is bacteriostatic.

Many sulphonamides are rapidly excreted and very soluble in urine so they are used to treat infections of the urinary tract.

List of Sulfonamides:

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Drug Name DownUp( View by: Brand | Generic ) Reviews Ratings DownUp
sulfamethoxazole / trimethoprim systemic (Pro, More...)
613 reviews
sulfadiazine systemic (Pro, More...)
0 reviews
sulfisoxazole systemic (More...)
0 reviews