Sulfur Hexafluoride Dosage

Usual Adult Dose for Diagnostic

2 mL IV bolus during echocardiography

Comments:
-Reconstitute prior to administration; consult manufacturer product information.
-Follow each injection with a 5 mL IV flush of 0.9% sodium chloride.
-A second 2 mL IV bolus of drug may be given during a single examination to prolong contrast enhancement.

Use: To opacify the left ventricular chamber and improve the delineation of the left ventricular endocardial border in patients with suboptimal echocardiograms

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

US BOXED WARNING:
-SERIOUS CARDIOPULMONARY REACTIONS: Serious cardiopulmonary reactions, including fatalities, have occurred uncommonly during or following the injection of ultrasound contrast agents, including sulfur hexafluoride lipid microspheres. Most serious reactions occur within 30 minutes of administration. Assess all patients for the presence of any condition that precludes administration. Always have resuscitation equipment and trained personnel readily available.

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-For single use only; discard unused portions appropriately.
-Do not administer by intra-arterial injection.