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Rezipres Dosage

Generic name: EPHEDRINE HYDROCHLORIDE 4.7mg in 1mL
Dosage form: injection, solution
Drug class: Vasopressors

Medically reviewed by Drugs.com. Last updated on Aug 1, 2021.

General Dosage and Administration Instructions

REZIPRES® 47 mg/mL must be diluted before administration as an intravenous bolus to achieve the desired concentration. Dilute with normal saline or 5% dextrose in water.


REZIPRES® 9.4 mg/mL can be either used as provided at 9.4 mg/mL or it can be diluted, with 5% Dextrose Injection or 0.9% Sodium Chloride Injection, to achieve the desired concentration, before administration as an intravenous bolus.


REZIPRES® 4.7 mg/mL is a premixed formulation. Do not dilute prior to use.

  • REZIPRES® is a clear, colorless solution. Discard any unused portion.
  • Inspect parenteral drug products visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Do not use if the solution is not clear or if particulate matter is present.

Dosing for Treatment of Clinically Important Hypotension in the Setting of Anesthesia

The recommended dosages for the treatment of clinically important hypotension in the setting of anesthesia is an initial dose of 4.7 mg to 9.4 mg administered by intravenous bolus. Administer additional boluses as needed, not to exceed a total dosage of 47 mg.

  • Adjust dosage according to the blood pressure goal (i.e., titrate to effect).

Prepare a 4.7 mg/mL Solution for Bolus Intravenous Administration

REZIPRES® 47 mg/mL

• Withdraw 47 mg (1 mL of 47 mg/mL) of REZIPRES® 47 mg/mL and dilute with 9 mL of 5% Dextrose Injection or 0.9% Sodium Chloride Injection.
• Withdraw an appropriate dose of the 4.7 mg/mL solution prior to bolus intravenous administration.

REZIPRES® 9.4 mg/mL
• Withdraw 5 mL of REZIPRES® 9.4 mg/mL and dilute with 5 mL of 5% Dextrose Injection or 0.9% Sodium Chloride Injection.
• Withdraw an appropriate dose of the 4.7 mg/mL solution prior to bolus intravenous administration.

Direct Administration of 9.4 mg/mL Solution for Bolus Intravenous

REZIPRES® if used as provided at 9.4 mg/ml:
• withdraw an appropriate dose of REZIPRES® 9.4 mg/mL solution prior to bolus intravenous administration.

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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.