Namenda Dosage
Generic name: MEMANTINE HYDROCHLORIDE 5mg
Dosage form: tablet, oral solution
Drug class: Miscellaneous central nervous system agents
Medically reviewed by Drugs.com. Last updated on Oct 22, 2024.
The recommended starting dose of NAMENDA is 5 mg once daily. The dose should be increased in 5 mg increments to 10 mg/day (5 mg twice daily), 15 mg/day (5 mg and 10 mg as separate doses), and 20 mg/day (10 mg twice daily). The minimum recommended interval between dose increases is one week. The dosage shown to be effective in controlled clinical trials is 20 mg/day.
NAMENDA can be taken with or without food. If a patient misses a single dose of NAMENDA, that patient should not double up on the next dose. The next dose should be taken as scheduled.
If a patient fails to take NAMENDA for several days, dosing may need to be resumed at lower doses and retitrated as described above.
Specific Populations
Renal Impairment
A target dose of 5 mg twice daily is recommended in patients with severe renal impairment (creatinine clearance of 5 – 29 mL/min based on the Cockcroft-Gault equation).
Hepatic Impairment
NAMENDA should be administered with caution to patients with severe hepatic impairment.
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Further information
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