Measles Virus Vaccine / Mumps Virus Vaccine / Rubella Virus Vaccine / Varicella Virus Vaccine Dosage

Medically reviewed by Drugs.com. Last updated on Sep 5, 2023.

Usual Pediatric Dose for Varicella-Zoster - Prophylaxis

1 to 12 years:
1 dose (0.5 mL) intramuscularly or subcutaneously in the outer deltoid or higher anterolateral thigh

Comments:

• The first dose is usually administered at 12 to 15 months of age.
• A second dose, if needed, is usually administered at 4 to 6 years of age.

Use: Active immunization for the prevention of measles, mumps, rubella, and varicella in children 12 months through 12 years of age

Usual Pediatric Dose for Vaccination

1 to 12 years:
1 dose (0.5 mL) intramuscularly or subcutaneously in the outer deltoid or higher anterolateral thigh

Comments:

• The first dose is usually administered at 12 to 15 months of age.
• A second dose, if needed, is usually administered at 4 to 6 years of age.

Use: Active immunization for the prevention of measles, mumps, rubella, and varicella in children 12 months through 12 years of age

Usual Pediatric Dose for Mumps Prophylaxis

1 to 12 years:
1 dose (0.5 mL) intramuscularly or subcutaneously in the outer deltoid or higher anterolateral thigh

Comments:

• The first dose is usually administered at 12 to 15 months of age.
• A second dose, if needed, is usually administered at 4 to 6 years of age.

Use: Active immunization for the prevention of measles, mumps, rubella, and varicella in children 12 months through 12 years of age

Usual Pediatric Dose for Rubella Prophylaxis

1 to 12 years:
1 dose (0.5 mL) intramuscularly or subcutaneously in the outer deltoid or higher anterolateral thigh

Comments:

• The first dose is usually administered at 12 to 15 months of age.
• A second dose, if needed, is usually administered at 4 to 6 years of age.

Use: Active immunization for the prevention of measles, mumps, rubella, and varicella in children 12 months through 12 years of age

Usual Pediatric Dose for Measles Prophylaxis

1 to 12 years:
1 dose (0.5 mL) intramuscularly or subcutaneously in the outer deltoid or higher anterolateral thigh

Comments:

• The first dose is usually administered at 12 to 15 months of age.
• A second dose, if needed, is usually administered at 4 to 6 years of age.

Use: Active immunization for the prevention of measles, mumps, rubella, and varicella in children 12 months through 12 years of age

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

• Anaphylactic reaction to neomycin. If vaccination is medically necessary, consult an allergist or immunologist and administer only where anaphylactic reactions can be appropriately managed
• Hypersensitivity to any of the ingredients, gelatin, or other measles-, mumps-, or rubella-containing vaccine
• Immunosuppression: Do not administer to patients with blood dyscrasias, leukemia, any type of lymphoma or other malignant neoplasm affecting the bone or lymph system, and patients on immunosuppressive therapy, including high-dose systemic corticosteroids. Live, attenuated vaccines like varicella can cause more extensive rash or disseminated disease in immunosuppressed individuals
• This vaccine may be used in patients on topical or low-dose corticosteroids such as those commonly used for asthma or prophylaxis therapy (e.g., for Addison's disease)
• Primary or acquired immunodeficiency, including AIDS or manifestations of human immunodeficiency virus infection, cellular immune deficiencies, and hypogammaglobulinemia, and dysgammaglobulinemia. Measles including body encephalitis, pneumonitis, and death because of disseminated measles vaccine virus infection have occurred in severely immunocompromised individuals and immunodeficient children inadvertently given measles containing vaccine
• Family history of congenital or hereditary immunodeficiency unless immune competence is demonstrated
• Active untreated tuberculosis or active febrile illness with fever over 101.3 F
• Pregnancy: Fetal effects are unknown. Pregnancy should be avoided for 3 months following vaccination

Safety and efficacy have not been established in patients younger than 12 months or older than 12 years.

To report suspected adverse reactions, contact the Vaccine Adverse Event Reporting System (VAERS) at: https://vaers.hhs.gov

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• A month should elapse between a dose of a measles-containing vaccine and this product.
• Three months should elapse between a dose of varicella-containing vaccine and this product.
• Visually inspect the product for particulate matter and discoloration before administration.
• Do not use if particulates are present or if it appears discolored.
• Immediately administer the vaccine after reconstitution. If not used immediately, store it at room temperature for up to 30 minutes, protected from light.
• Discard reconstituted vaccine if it is not used within 30 minutes.
• Do not freeze reconstituted vaccine.

Storage requirements:

• Store in a freezer between -58 F and +5F (-50C to -15C).
• Vaccine may be stored refrigerated at 36F to 46F (2 to 8C) for up to 72 hours prior to reconstitution.
• Protect the vaccine from light.

Reconstitution/preparation techniques:

• Use a sterile syringe and diluent free of preservatives, antiseptics, and detergents for each injection and to reconstitute the vaccine.
• Inject diluent into the lyophilized vaccine vial. Agitate until completely dissolved and discard if the lyophilized vaccine cannot be dissolved.
• The manufacturer product information should be consulted.

Patient advice:

• Read the US FDA-approved patient labeling (Patient Information and Instructions for Use).
• Avoid use of salicylates for 6 weeks after vaccination.
• Avoid pregnancy for 3 months after vaccination.
• This vaccine may not offer 100% protection from measles, mumps, rubella, and varicella infection.
• Report any adverse reactions to your health care provider.

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer