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Macimorelin Dosage

Medically reviewed by Last updated on Sep 7, 2021.

Applies to the following strengths: 60 mg

Usual Adult Dose for Growth Hormone Reserve Test

0.5 mg/kg orally, after fasting for at least 8 hours


  • Discontinue therapy with strong CYP450 3A4 inducers, growth hormones, and drugs affecting growth hormone release for an adequate length of time before administration of this drug.
  • Adequately replace other hormone deficiencies before administration.
  • Safety and diagnostic performance have not been established in patients with a body mass index over 40 kg/m2.

Use(s): Diagnosis of adult growth hormone deficiency

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:

  • Must be reconstituted by a health care professional prior to consumption.
  • The patient must fast for at least 8 hours prior to administration.

Storage requirements: Refrigerate

Reconstitution/preparation techniques:
  • This product must be reconstituted prior to administration.
  • The manufacturer product information should be consulted.
  • The solution must be used within 30 minutes after preparation.

  • Maximally stimulated serum growth hormone levels of less than 2.8 ng/mL (i.e. at the 30, 45, 60, and 90 minute timepoints) after drug administration confirms adult growth hormone deficiency.

Patient advice:
  • Instruct patients to discontinue growth hormone at least one week before administering this drug, and to discontinue other medications that may interfere with diagnostic test results prior to administration.
  • Instruct patients to fast for at least 8 hours before administration.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.