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Macimorelin Side Effects

Medically reviewed by Last updated on Aug 22, 2022.

Applies to macimorelin: oral granule.

Serious side effects of Macimorelin

Along with its needed effects, macimorelin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking macimorelin:

Less common

Other side effects of Macimorelin

Some side effects of macimorelin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

For Healthcare Professionals

Applies to macimorelin: oral granule for reconstitution.


Common (1% to 10%): Sinus bradycardia[Ref]


Common (1% to 10%): Dysgeusia, nausea, diarrhea[Ref]

Nervous system

Common (1% to 10%): Dizziness, headache[Ref]


Common (1% to 10%): Upper respiratory tract infection, nasopharyngitis[Ref]


Common (1% to 10%): Fatigue, feeling hot[Ref]


Common (1% to 10%): Hunger[Ref]


Common (1% to 10%): Hyperhidrosis[Ref]


1. "Product Information. Macrilen (macimorelin)." Aeterna Zentaris (2018):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.