Levofloxacin Ophthalmic Dosage

Usual Adult Dose for Bacterial Conjunctivitis

0.5% solution:
-Days 1 and 2: Instill 1 to 2 drops in the affected eye(s) every 2 hours while awake, up to 8 times a day.
-Days 3 through 7: Instill 1 to 2 drops in the affected eye(s) every 4 hours while awake, up to 4 times a day.

Use: For the treatment of bacterial conjunctivitis caused by susceptible strains of Corynebacterium species, Staphylococcus aureus, S epidermidis, Streptococcus pneumonia, Streptococcus (groups C/F), Streptococcus (group G), viridans group streptococci, Acinetobacter lwoffii, Haemophilus influenzae, Serratia marcescens

Usual Adult Dose for Corneal Ulcers

1.5% solution:
-Days 1 through 3: Instill 1 to 2 drops in the affected eye(s) every 30 minutes to 2 hours while awake and approximately 4 and 6 hours after retiring.
-Day 4 through treatment completion: Instill 1 to 2 drops in the affected eye(s) every 1 to 4 hours while awake.

Use: For the treatment of corneal ulcer due to susceptible strains of Corynebacterium species, S aureus, S epidermidis, S pneumonia, viridans group streptococci, S marcescens, Pseudomonas aeruginosa

Usual Pediatric Dose for Bacterial Conjunctivitis

6 years or older:
0.5% solution:
-Days 1 and 2: Instill 1 to 2 drops in the affected eye(s) every 2 hours while awake, up to 8 times a day.
-Days 3 through 7: Instill 1 to 2 drops in the affected eye(s) every 4 hours while awake, up to 4 times a day.

Use: For the treatment of bacterial conjunctivitis caused by susceptible strains of Corynebacterium species, S aureus, S epidermidis, S pneumonia, Streptococcus (groups C/F), Streptococcus (group G), viridans group streptococci, A lwoffii, H influenzae, S marcescens

Usual Pediatric Dose for Corneal Ulcers

6 years or older:
1.5% solution:
-Days 1 through 3: Instill 1 to 2 drops in the affected eye(s) every 30 minutes to 2 hours while awake and approximately 4 and 6 hours after retiring.
-Day 4 through treatment completion: Instill 1 to 2 drops in the affected eye(s) every 1 to 4 hours while awake.

Use: For the treatment of corneal ulcer due to susceptible strains of Corynebacterium species, S aureus, S epidermidis, S pneumonia, viridans group streptococci, S marcescens, P aeruginosa

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Safety and efficacy have not been established in patients younger than 6 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Storage requirements:
-Store at 15C to 25C (59F to 77F).

Patient advice:
-Do not wear contact lenses if you have signs/symptoms of bacterial conjunctivitis or corneal ulcers.
-Avoid contaminating the applicator tip with material from the eye, fingers, or any other source.
-Stop this drug and seek medical attention immediately at the first sign of a rash or allergic reaction.