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Gentamicin Ophthalmic Dosage

Medically reviewed by Drugs.com. Last updated on Aug 21, 2023.

Applies to the following strengths: 0.3%

Usual Adult Dose for Bacterial Conjunctivitis

Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, Serratia marcescens, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, and/or Streptococcus pyogenes

Usual Adult Dose for Corneal Ulcers

Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, Serratia marcescens, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, and/or Streptococcus pyogenes

Usual Adult Dose for Keratitis

Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, Serratia marcescens, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, and/or Streptococcus pyogenes

Usual Adult Dose for Keratoconjunctivitis

Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, Serratia marcescens, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, and/or Streptococcus pyogenes

Usual Adult Dose for Blepharitis

Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, Serratia marcescens, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, and/or Streptococcus pyogenes

Usual Adult Dose for Blepharoconjunctivitis

Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, Serratia marcescens, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, and/or Streptococcus pyogenes

Usual Adult Dose for Acute Meibomianitis

Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, Serratia marcescens, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, and/or Streptococcus pyogenes

Usual Adult Dose for Dacryocystitis

Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, Serratia marcescens, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, and/or Streptococcus pyogenes

Usual Adult Dose for Conjunctivitis

Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, Serratia marcescens, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, and/or Streptococcus pyogenes

Usual Pediatric Dose for Bacterial Conjunctivitis

Children (1 month and older):
Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of E aerogenes, E coli, H influenzae, K pneumoniae, N gonorrhoeae, P aeruginosa, S marcescens, S aureus, S epidermidis, S pneumoniae, and/or S pyogenes

Usual Pediatric Dose for Corneal Ulcers

Children (1 month and older):
Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of E aerogenes, E coli, H influenzae, K pneumoniae, N gonorrhoeae, P aeruginosa, S marcescens, S aureus, S epidermidis, S pneumoniae, and/or S pyogenes

Usual Pediatric Dose for Keratitis

Children (1 month and older):
Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of E aerogenes, E coli, H influenzae, K pneumoniae, N gonorrhoeae, P aeruginosa, S marcescens, S aureus, S epidermidis, S pneumoniae, and/or S pyogenes

Usual Pediatric Dose for Keratoconjunctivitis

Children (1 month and older):
Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of E aerogenes, E coli, H influenzae, K pneumoniae, N gonorrhoeae, P aeruginosa, S marcescens, S aureus, S epidermidis, S pneumoniae, and/or S pyogenes

Usual Pediatric Dose for Blepharitis

Children (1 month and older):
Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of E aerogenes, E coli, H influenzae, K pneumoniae, N gonorrhoeae, P aeruginosa, S marcescens, S aureus, S epidermidis, S pneumoniae, and/or S pyogenes

Usual Pediatric Dose for Blepharoconjunctivitis

Children (1 month and older):
Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of E aerogenes, E coli, H influenzae, K pneumoniae, N gonorrhoeae, P aeruginosa, S marcescens, S aureus, S epidermidis, S pneumoniae, and/or S pyogenes

Usual Pediatric Dose for Acute Meibomianitis

Children (1 month and older):
Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of E aerogenes, E coli, H influenzae, K pneumoniae, N gonorrhoeae, P aeruginosa, S marcescens, S aureus, S epidermidis, S pneumoniae, and/or S pyogenes

Usual Pediatric Dose for Dacryocystitis

Children (1 month and older):
Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of E aerogenes, E coli, H influenzae, K pneumoniae, N gonorrhoeae, P aeruginosa, S marcescens, S aureus, S epidermidis, S pneumoniae, and/or S pyogenes

Usual Pediatric Dose for Conjunctivitis

Children (1 month and older):
Ophthalmic ointment: Apply a small amount (approximately a 1.27 cm-long ribbon) to the affected eye(s) 2 to 3 times a day

Ophthalmic solution: 1 to 2 drops into the affected eye(s) every 4 hours


Comments:

Use: Topical treatment of ocular bacterial infections (e.g., acute meibomianitis, blepharitis, blepharoconjunctivitis, conjunctivitis, corneal ulcers, dacryocystitis, keratitis, keratoconjunctivitis) caused by susceptible strains of E aerogenes, E coli, H influenzae, K pneumoniae, N gonorrhoeae, P aeruginosa, S marcescens, S aureus, S epidermidis, S pneumoniae, and/or S pyogenes

Usual Pediatric Dose for Surgical Prophylaxis

American Academy of Pediatrics Recommendations: Apply multiple drops to the affected eye(s) 2 to 24 hours prior to the procedure

Comment: Susceptibility of isolates should be considered when determining treatment.

Use: Preoperative antimicrobial prophylaxis in neonatal patients older than 72 hours and children undergoing ophthalmic procedures with the following likely pathogens: Enteric gram-negative bacilli, Pseudomonas species, S aureus, S epidermidis, and/or streptococci

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:


NARROW THERAPEUTIC INDEX:
Recommendations:

Safety and efficacy have not been established in neonates.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


Storage requirements:

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.