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Dextromethorphan / Phenylephrine Dosage

Medically reviewed by Last updated on Dec 28, 2020.

Applies to the following strengths: 2.5 mg-1.25 mg/0.8 mL; 5 mg-2.5 mg/5 mL; 5 mg-2.5 mg; 30 mg-5 mg/10 mL

Usual Pediatric Dose for Cough and Nasal Congestion

Dextromethorphan 5 mg/ phenylephrine 2.5 mg per 5 mL liquid:
6 to under 12 years: 10 mL every 4 hours
4 to under 6 years: 5 mL every 4 hours
Maximum dose: 6 doses per 24 hours

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available


-Current use of a monoamine oxidase inhibitor (MAOI) or use within 14 days of stopping a MAOI.
-Use in children under 4 years old

Safety and efficacy have not been established in patients younger than 4 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:
-Use only the provided dosing cups for measuring.

Patient advice:
-Take only as directed.
-Discontinue for nervousness, dizziness, or sleepiness.
-If symptoms last over 7 days or are accompanied by fever, seek medical attention.
-If cough lasts over 7 days or comes back, or is accompanied or followed by fever, headache that lasts, or rash, seek medical care promptly.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.