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Dextromethorphan / phenylephrine Pregnancy and Breastfeeding Warnings

Dextromethorphan / phenylephrine is also known as: Albatussin Pediatric, Albatussin Pediatric Drops, Children's Triacting Daytime, Dimetapp Toddler's Drops Decongestant Plus Cough, Little Colds Decongestant/Cough, PediaCare Children's Multi-Symptom Cold, PediaCare Daytime Multi-Symptom Cold, Safetussin CD, Sudafed PE Children's Cold & Cough, Theraflu Thin Strips Daytime Cold and Cough, Triaminic Day Time Cold & Cough, Triaminic Thin Strips Day Time Cold & Cough, Vicks Formula 44 Custom Care Congestion

Dextromethorphan / phenylephrine Pregnancy Warnings

Dextromethorphan has been assigned to pregnancy category C by the FDA. Animal studies have revealed evidence of teratogenicity. There are no controlled data in human pregnancy. Phenylephrine has been assigned to pregnancy category C by the FDA. Animal studies have not been reported. There are no controlled data in human pregnancy. Dextromethorphan-phenylephrine is only recommended for use during pregnancy when benefit outweighs risk.

See references

Dextromethorphan / phenylephrine Breastfeeding Warnings

There are no data on the excretion of dextromethorphan into human milk. Small amounts of phenylephrine are secreted in breast milk. The manufacturer recommends that due to the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

See references

References for pregnancy information

  1. Debus O, Kurlemann G, Gehrmann J, Krasemann T "Dextromethorphan in pregnancy." Chest 120 (2001): 1038-40
  2. Einarson A, Lyszkiewicz D, Koren G "The safety of dextromethorphan in pregnancy - Results of a controlled study." Chest 119 (2001): 466-9
  3. "Product Information. Lusonal (phenylephrine)." Wraser Pharmaceuticals, Ridgeland, MS.
  4. Andaloro VJ, Monaghan DT, Rosenquist TH "Dextromethorphan and other N-methyl-D-aspartate receptor antagonists are teratogenic in the avian embryo model." Pediatr Res 43 (1998): 1-7
  5. "Product Information. Benylin DM (dextromethorphan)." Warner Lambert Laboratories, Morris Plains, NJ.
  6. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):

References for breastfeeding information

  1. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):
  2. "Product Information. Benylin DM (dextromethorphan)." Warner Lambert Laboratories, Morris Plains, NJ.
  3. "Product Information. Lusonal (phenylephrine)." Wraser Pharmaceuticals, Ridgeland, MS.

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