Corticorelin Dosage

Usual Adult Dose for Cushing's Syndrome

Maintenance dose: 1 mcg/kg intravenously over 30 seconds once
Maximum dose: Doses greater than 1 mcg/kg are not recommended.

Comments: Some adverse effects can be reduced by administering the drug as an infusion over 30 seconds instead of as a bolus injection.

Use: Differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome.

Usual Pediatric Dose for Cushing's Syndrome

Maintenance dose: 1 mcg/kg intravenously over 30 seconds once
Maximum dose: Doses greater than 1 mcg/kg are not recommended.

Comments: Some adverse effects can be reduced by administering the drug as an infusion over 30 seconds instead of as a bolus injection.

Use: Differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-For intravenous injection only

Reconstitution/preparation techniques:
-The manufacturer product information should be consulted.

General:
-If a repeated evaluation is needed, the repeat test should be carried out at the same time of day as the original test.
-Do not shake.