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Acthrel (Intravenous)

Generic Name: corticorelin ovine triflutate (Intravenous route)

kor-ti-koe-REL-in OH-vine TRYE-floo-tate

Medically reviewed on Oct 4, 2018

Commonly used brand name(s)

In the U.S.

  • Acthrel

Available Dosage Forms:

  • Powder for Solution

Therapeutic Class: Diagnostic Agent

Uses For Acthrel

Corticorelin ovine triflutate injection is used as part of a test to identify Cushing syndrome.

This medicine is to be given by or under the supervision of your doctor.

Before Using Acthrel

In deciding to use a diagnostic test, any risks of the test must be weighed against the good it will do. This is a decision you and your doctor will make. Also, other things may affect test results. For this test, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Acthrel® in children.

Geriatric

No information is available on the relationship of age to the effects of Acthrel® in geriatric patients.

Pregnancy

Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of Acthrel

A nurse or other trained health professional will give you this medicine in a hospital. This medicine is given through a needle placed in one of your veins.

Precautions While Using Acthrel

Your doctor will check your progress closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it. Blood tests may be needed to check for unwanted effects.

Allergic reactions may occur while you are receiving this medicine. Tell your doctor right away if you have a rash or itching skin, flushing or redness of the face, neck, and upper chest, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs, or trouble breathing.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Acthrel Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

  • Difficult or labored breathing
  • feeling of warmth
  • hives or welts, itching, or skin rash
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • redness of the skin
  • redness of the face, neck, arms, and occasionally, upper chest
  • tightness in the chest

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  • Difficult or labored breathing
  • severe redness of the face

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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