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Acthrel Side Effects

Generic Name: corticorelin

Note: This page contains information about the side effects of corticorelin. Some of the dosage forms included on this document may not apply to the brand name Acthrel.

For the Consumer

Applies to corticorelin: intravenous powder for solution

In addition to its needed effects, some unwanted effects may be caused by corticorelin (the active ingredient contained in Acthrel). In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking corticorelin, check with your doctor or nurse immediately:

Incidence not known:
  • Difficult or labored breathing
  • feeling of warmth
  • hives or welts, itching, or skin rash
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • redness of the skin
  • redness of the face, neck, arms, and occasionally, upper chest
  • tightness in the chest

If any of the following symptoms of overdose occur while taking corticorelin, get emergency help immediately:

Symptoms of overdose:
  • Difficult or labored breathing
  • severe redness of the face

For Healthcare Professionals

Applies to corticorelin: intravenous powder for injection


Very common (10% or more): Flushing of the face, neck, and upper chest (16%)
Common (1% to 10%): Asystole
Frequency not reported: Prolonged flushing, tachycardia, hypotension, "chest compression" or tightness, increases in heart rate, decreases in blood pressure, transient flushing[Ref]


The most commonly reported side effects were flushing of the face, neck, and upper chest.[Ref]

Nervous system

Common (1% to 10%): "Absence-like" loss of consciousness, grand mal epileptic seizure[Ref]


Common (1% to 10%): Urge to take a deep breath
Frequency not reported: Dyspnea[Ref]


1. "Product Information. Acthrel (corticorelin)." Ferring Laboratories Inc, Tarrytown, NY.

Not all side effects for Acthrel may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.