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Acthrel Side Effects

Generic name: corticorelin

Medically reviewed by Last updated on Sep 14, 2023.

Note: This document contains side effect information about corticorelin. Some dosage forms listed on this page may not apply to the brand name Acthrel.

Applies to corticorelin: intravenous solution reconstituted.

Serious side effects of Acthrel

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

Other side effects of Acthrel

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if you have any side effects that bother you or do not go away.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at

For Healthcare Professionals

Applies to corticorelin: intravenous powder for injection.


Very common (10% or more): Flushing of the face, neck, and upper chest (16%)

Common (1% to 10%): Asystole

Frequency not reported: Prolonged flushing, tachycardia, hypotension, "chest compression" or tightness, increases in heart rate, decreases in blood pressure, transient flushing[Ref]


The most commonly reported side effects were flushing of the face, neck, and upper chest.[Ref]

Nervous system

Common (1% to 10%): "Absence-like" loss of consciousness, grand mal epileptic seizure[Ref]


Common (1% to 10%): Urge to take a deep breath

Frequency not reported: Dyspnea[Ref]


1. Product Information. Acthrel (corticorelin). Ferring Pharmaceuticals Inc. 2001;PROD.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.