Calcium Gluceptate Dosage
Applies to the following strengths: 220 mg/mL
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Hypocalcemia
1.1 to 4.4 g (5 to 20 mL) IV once slowly, less than 2 mL/min. This dose may be repeated every 1 to 3 days as needed and tolerated to normalize the serum calcium level.
0.44 to 1.1 g (2 to 5 mL) IM once. This dose may be repeated every 1 to 3 days as needed and tolerated to normalize the serum calcium level.
Usual Pediatric Dose for Hypocalcemia
Child: 200 to 500 mg (1 to 2.5 mL) IV once.
Usual Pediatric Dose for Exchange Transfusion
Exchange transfusions in newborns:
110 mg (0.5 mL) IV once after every 100 mL of blood exchanged
Renal Dose Adjustments
Patients with renal dysfunction have an increased risk of hypercalcemia. Periodically checking the serum calcium level, especially if signs or symptoms of hypercalcemia are detected, is recommended.
Liver Dose Adjustments
Data not available
Calcium gluceptate is contraindicated in patients with hypercalcemia, ventricular fibrillation, and in patients receiving digitalis preparations.
Calcium is removed by hemodialysis. To ensure a positive net calcium flux into the patient during dialysis, a dialysate calcium concentration of 3 to 3.5 mEq/L is usually required. Mid-dialysis modest hypercalcemia in not uncommon when this concentration is used.
Calcium is removed by peritoneal dialysis. The standard peritoneal dialysate contains 3.5 mEq/L of calcium (in 1.5% dextrose) to maintain a positive calcium balance and to prevent calcium loses. When higher concentrations of dextrose are used, the net calcium balance may be negative because of a greater convective removal of calcium during ultrafiltration, which counterbalances the diffusion of calcium from the dialysate to the patient.
The recommended daily allowance (RDA) of calcium for adults is 800 mg. The RDA for pregnant or lactating women is 1,200 mg. Each 1 g of calcium gluceptate contains 82 mg elemental calcium, or 4.1 mEq of calcium.