Calcium Chloride Dosage

Usual Adult Dose for Hypocalcemia

Usual dose: 500 to 1000 mg by slow intravenous injection, every 1 to 3 days depending on response and/or serum calcium

• Repeat injections may be needed because of rapid calcium excretion.

Maximum rate: 1 mL/min

Use: Hypocalcemia in conditions requiring prompt blood calcium increases

Usual Adult Dose for Hypermagnesemia

Initial dose: 500 mg by slow intravenous injection
Maximum rate: 1 mL/min

Comments:

• Give dose promptly.
• Observe for signs of recovery before administering additional doses.

Use: Magnesium toxicity due to magnesium sulfate overdose

Usual Adult Dose for Hyperkalemia

Dose is titrated by constant ECG monitoring
Maximum rate: 1 mL/min

Use: To combat deleterious effects of hyperkalemia as measured by electrocardiograph (ECG) pending correction of increased extracellular potassium

Usual Adult Dose for Asystole

Usual dose:
500 to 1000 mg by slow intravenous injection
Maximum rate: 1 mL/min

OR

200 to 800 mg injected into the ventricular cavity

Comments:

• Do not inject into the myocardium.

Use: Cardiac resuscitation when weak or inadequate contractions return after defibrillation, or when epinephrine has not strengthened myocardial contractions

Usual Adult Dose for Electromechanical Dissociation

Usual dose:
500 to 1000 mg by slow intravenous injection
Maximum rate: 1 mL/min

OR

200 to 800 mg injected into the ventricular cavity

Comments:

• Do not inject into the myocardium.

Use: Cardiac resuscitation when weak or inadequate contractions return after defibrillation, or when epinephrine has not strengthened myocardial contractions

Renal Dose Adjustments

Data not available

• This product contains aluminum, which may become toxic with prolonged parenteral administration in patients with impaired renal function.
• Premature neonates are at increased risk for aluminum toxicity due to their immature kidneys and need for large calcium and phosphate doses, which contain aluminum.
• Patients, including premature neonates, with impaired kidney function who receive over 4 to 5 mcg/kg/day aluminum have accumulation levels associated with central nervous system and bone toxicity; tissue loading may occur at lower administration rates also.

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

• Contraindicated for cardiac resuscitation if ventricular fibrillation or digitalis toxicity are present

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Use great care to avoid extravasation or perivascular injection.
• Inject slowly using a small needle in a large vein to minimize irritation and reduce adverse event risk.
• This drug must not be injected into the myocardial tissue; only inject into the ventricular cavity during cardiac resuscitation.
• Halt injections for patient discomfort; infusion may be continued after discomfort subsides.
• The patient should remain recumbent for a short time after the infusion.

Reconstitution/preparation techniques:

• Warm to body temperature if time permits
• Inspect for particulates and discoloration

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer