Benzgalantamine Dosage
Medically reviewed by Drugs.com. Last updated on Apr 30, 2025.
Applies to the following strengths: 5 mg; 10 mg; 15 mg
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Alzheimer's Disease
Initial dose: 5 mg orally twice a day
Maintenance dose: Increase to 10 mg orally twice a day after at least 4 weeks of therapy, based on response and tolerability
Maximum dose: 15 mg orally twice a day after at least 4 weeks of treatment at 10 mg twice a day
Use: For the treatment of mild to moderate dementia of Alzheimer's type
Renal Dose Adjustments
CrCl 9 to less than 59 mL/min: Maximum recommended dose of 10 mg orally twice a day.
CrCl less than 9 mL/min: Not recommended.
Liver Dose Adjustments
Mild liver dysfunction (Child-Pugh Score 5 to 6): No adjustment recommended.
Moderate liver dysfunction (Child-Pugh Score 7 to 9): Maximum recommended dose of 10 mg orally twice a day.
Severe liver dysfunction (Child-Pugh Score 10 to 15): Not recommended.
Precautions
CONTRAINDICATIONS:
- Known hypersensitivity to the active component, galantamine, or to any of the ingredients; serious skin reactions have occurred.
Safety and efficacy have not been established in patients younger than 18 years.
Consult WARNINGS section for additional precautions.
Dialysis
Hemodialysis: Unknown
Peritoneal dialysis: Unknown
Other Comments
Administration advice:
- For oral use
- Administer with or without food.
- Swallow tablets whole; do not split, crush or chew.
- Adequate fluid intake is recommended during treatment.
- This drug should not be taken with alcohol.
- Missed dose(s): If therapy is interrupted for more than 3 days, treatment should be restarted at the lowest dosage and then titrated to the current dose.
Storage requirements:
- Store at 68F to 77F (20C to 25C); excursions permitted between 59F to 86F (15C to 30C).
Monitoring:
- Cardiovascular: For cardiac conduction abnormalities (during therapy)
- Gastrointestinal: For active or occult bleeding (during therapy, especially in patients at increased risk for developing ulcers)
- General: For weight loss (during therapy)
- Neurologic: For seizures in patients with Alzheimer's disease (during therapy)
- Respiratory: Respiratory function (during therapy, especially in patients with a history of pulmonary conditions)
Patient advice:
- Read the US FDA-approved patient labeling (Medication Guide or Patient Information).
- Seek immediate medical attention and discontinue therapy at the first appearance of skin rash.
- Ensure adequate hydration during treatment; do not take this drug with alcohol.
- Patients of childbearing potential: Notify your health care provider of a known/suspected pregnancy.
More about benzgalantamine
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- Drug class: cholinesterase inhibitors
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.