Benzgalantamine Dosage

Medically reviewed by Drugs.com. Last updated on Apr 30, 2025.

Usual Adult Dose for Alzheimer's Disease

Initial dose: 5 mg orally twice a day
Maintenance dose: Increase to 10 mg orally twice a day after at least 4 weeks of therapy, based on response and tolerability
Maximum dose: 15 mg orally twice a day after at least 4 weeks of treatment at 10 mg twice a day

Use: For the treatment of mild to moderate dementia of Alzheimer's type

Renal Dose Adjustments

CrCl 9 to less than 59 mL/min: Maximum recommended dose of 10 mg orally twice a day.
CrCl less than 9 mL/min: Not recommended.

Liver Dose Adjustments

Mild liver dysfunction (Child-Pugh Score 5 to 6): No adjustment recommended.
Moderate liver dysfunction (Child-Pugh Score 7 to 9): Maximum recommended dose of 10 mg orally twice a day.
Severe liver dysfunction (Child-Pugh Score 10 to 15): Not recommended.

Precautions

CONTRAINDICATIONS:

• Known hypersensitivity to the active component, galantamine, or to any of the ingredients; serious skin reactions have occurred.

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Hemodialysis: Unknown
Peritoneal dialysis: Unknown

Other Comments

Administration advice:

• For oral use
• Administer with or without food.
• Swallow tablets whole; do not split, crush or chew.
• Adequate fluid intake is recommended during treatment.
• This drug should not be taken with alcohol.
• Missed dose(s): If therapy is interrupted for more than 3 days, treatment should be restarted at the lowest dosage and then titrated to the current dose.

Storage requirements:

• Store at 68F to 77F (20C to 25C); excursions permitted between 59F to 86F (15C to 30C).

Monitoring:

• Cardiovascular: For cardiac conduction abnormalities (during therapy)
• Gastrointestinal: For active or occult bleeding (during therapy, especially in patients at increased risk for developing ulcers)
• General: For weight loss (during therapy)
• Neurologic: For seizures in patients with Alzheimer's disease (during therapy)
• Respiratory: Respiratory function (during therapy, especially in patients with a history of pulmonary conditions)

Patient advice:

• Read the US FDA-approved patient labeling (Medication Guide or Patient Information).
• Seek immediate medical attention and discontinue therapy at the first appearance of skin rash.
• Ensure adequate hydration during treatment; do not take this drug with alcohol.
• Patients of childbearing potential: Notify your health care provider of a known/suspected pregnancy.

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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