Tenecteplase Disease Interactions
There are 2 disease interactions with tenecteplase.
Tenecteplase -bleeding
Major Potential Hazard, Moderate plausibility. Applicable conditions: History - Cerebrovascular Disease, Hypertension, Brain/Intracranial Tumor, Head Injury
The most common complication encountered during tenecteplase therapy is bleeding. Tenecteplase therapy in patients with acute myocardial infarction is contraindicated in patients with active internal bleeding, history of cerebrovascular accident, intracranial or intraspinal surgery or trauma within 2 months, intracranial neoplasms, arteriovenous malformations or aneurysm, bleeding diathesis or severe uncontrolled hypertension, due to an increased risk of bleeding. Each patient being considered for therapy should be carefully evaluated and anticipated benefits weighed against potential risks associated with therapy.
Tenecteplase (applies to tenecteplase) thromboembolism
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Valvular Heart Disease, Arrhythmias
The use of tenecteplase can increase the risk of thromboembolic events in patients with high likelihood of left heart thrombus, such as patients with mitral stenosis or atrial fibrillation. Caution and monitoring is advised.
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Tenecteplase drug interactions
There are 154 drug interactions with tenecteplase.
Tenecteplase alcohol/food interactions
There is 1 alcohol/food interaction with tenecteplase.
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- tenecteplase consumer information
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- Side effects
- Dosage information
- During pregnancy
- Drug class: thrombolytics
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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