Tasimelteon Disease Interactions
There are 4 disease interactions with tasimelteon:
Anxiolytics/sedatives/hypnotics (applies to tasimelteon) depression
Major Potential Hazard, Moderate plausibility.
A variety of abnormal thinking and behavior changes have been reported to occur in association with the use of most anxiolytics, sedatives and hypnotics. Some of these changes include decreased inhibition, aggressiveness, agitation, and hallucinations. These drugs can cause or exacerbate mental depression and cause suicidal behavior and ideation. Therapy with these drugs should be administered cautiously in patients with a history of depression or other psychiatric disorders. Patients should be monitored for any changes in mood or behavior. It may be prudent to refrain from dispensing large quantities of medication to these patients.
- "Product Information. Ambien (zolpidem)." sanofi-aventis, Bridgewater, NJ.
- "Product Information. Sonata (zaleplon)" Wyeth-Ayerst Laboratories, Philadelphia, PA.
- "Product Information. Equanil (meprobamate)." Wallace Laboratories, Cranbury, NJ.
- "Product Information. Aquachloral Supprettes (chloral hydrate)." Medisca, Plattsburg, NY.
- "Product Information. Placidyl (ethchlorvynol)." Abbott Pharmaceutical, Abbott Park, IL.
Anxiolytics/sedatives/hypnotics (applies to tasimelteon) severe renal impairment
Major Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
Some anxiolytic, sedative and hypnotic drugs have not been studied in patients with severe renal impairment and should not be used on these patients.
Anxiolytics/sedatives/hypnotics (applies to tasimelteon) glaucoma
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Glaucoma/Intraocular Hypertension, Urinary Retention
Some hypnotic drugs can have an anticholinergic effect and should be used with caution in patients with glaucoma, and trouble urinating due to retention or enlarged prostate.
Anxiolytics/sedatives/hypnotics (applies to tasimelteon) liver disease
Moderate Potential Hazard, Moderate plausibility.
In general, anxiolytics, sedatives and hypnotics are extensively metabolized by the liver. Their plasma clearance may be decreased and their half-life prolonged in patients with impaired hepatic function. Therapy with these drugs should be administered cautiously in patients with liver disease (some are not recommended in severe liver impairment), and the dosage should be adjusted accordingly. Laboratory testing is recommended prior and during treatment.
Tasimelteon drug interactions
There are 375 drug interactions with tasimelteon
Tasimelteon alcohol/food interactions
There is 1 alcohol/food interaction with tasimelteon
More about tasimelteon
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- En Español
- Drug class: miscellaneous anxiolytics, sedatives and hypnotics
Related treatment guides
Drug Interaction Classification
|No interaction information available.|