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Lumason (sulfur hexafluoride) Disease Interactions

There is 1 disease interaction with Lumason (sulfur hexafluoride):

Major

Sulfur Hexafluoride (Includes Lumason) ↔ Cardiopulmonary Reactions

Severe Potential Hazard, High plausibility

Applies to: Heart Disease

Serious, potentially fatal cardiopulmonary reactions have infrequently occurred during or following the injection of ultrasound contrast agents including sulfur hexafluoride. Most serious reactions have been observed within 30 minutes of administration. Patients with unstable cardiopulmonary conditions such as acute myocardial infarction, acute coronary artery syndromes, worsening or unstable congestive heart failure, or serious ventricular arrhythmias may be at increased risk for developing these reactions. Patients receiving sulfur hexafluoride should be monitored for acute reactions including cardiac or respiratory arrest, shock, syncope, symptomatic arrhythmias (e.g., atrial fibrillation, tachycardia, bradycardia, supraventricular tachycardia, ventricular fibrillation, ventricular tachycardia), hypertension, hypotension, dyspnea, hypoxia, chest pain, respiratory distress, stridor, wheezing, loss of consciousness, and convulsions. Cardiopulmonary resuscitation personnel and equipment should be readily available at all times.

The use of sulfur hexafluoride lipid-type A microspheres injectable suspension is contraindicated in patients with known or suspected right-to-left, bi-directional, or transient right-to-left cardiac shunts. In such patients, concerns exist that some of the intravenously injected lipid-containing microspheres may bypass filtering by the lung and directly enter the arterial circulation. Occlusion of the microcirculation by these microspheres may result in tissue ischemia.

Lumason (sulfur hexafluoride) drug Interactions

There is 1 drug interaction with Lumason (sulfur hexafluoride)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.

Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.

Do not stop taking any medications without consulting your healthcare provider.

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