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Remdesivir Disease Interactions

There are 2 disease interactions with remdesivir.

Major

Remdesivir (applies to remdesivir) renal dysfunction

Major Potential Hazard, Moderate plausibility.

Pharmacokinetics of remdesivir have not been evaluated in patients with renal dysfunction. All patients must have estimated glomerular filtration rate (eGFR) determined before starting this drug and during therapy as clinically appropriate. The excipient betadex sulfobutyl ether sodium is renally cleared and accumulates in patients with reduced renal function; administration of drugs formulated with betadex sulfobutyl ether sodium (such as this drug) is not recommended in patients with eGFR less than 30 mL/min.

References

  1. "Product Information. Veklury (remdesivir)." Gilead Sciences (2020):
Moderate

Remdesivir (applies to remdesivir) liver dysfunction

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

Pharmacokinetics of remdesivir have not been evaluated in patients with liver dysfunction. Hepatic laboratory testing should be performed in all patients before starting this drug and during therapy as clinically appropriate. Caution is recommended.

References

  1. "Product Information. Veklury (remdesivir)." Gilead Sciences (2020):

Remdesivir drug interactions

There are 369 drug interactions with remdesivir.

Remdesivir alcohol/food interactions

There is 1 alcohol/food interaction with remdesivir.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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