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Podocon-25 Disease Interactions

There is 1 disease interaction with Podocon-25 (podophyllum resin topical).

Moderate

Podophyllum resin topical (applies to Podocon-25) CNS dysfunction

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Peripheral Neuropathy, Seizures

Podophyllum resin topical is systemically absorbed. Topical application of podophyllum resin has induced CNS toxicity ranging from confusion to coma, paresthesia and peripheral neuropathy, seizure, paralytic ileus, and death. Therapy with podophyllum resin topical should be applied cautiously in patients with impaired mental status, peripheral neuropathy, or seizure disorders.

References

  1. "Product Information. Podocon-25 (podophyllum resin topical)." Paddock Laboratories Inc PROD (2001):

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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