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Skyclarys Disease Interactions

There is 1 disease interaction with Skyclarys (omaveloxolone).

Moderate

Omaveloxolone (applies to Skyclarys) hepatic impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

Patients with severe liver dysfunction (Child-Pugh Class C) can have increased exposure to omaveloxolone and should avoid the use of this drug. Dosage adjustments and monitoring are required in patients with mild or moderate (Child-Pugh Class A or B) liver dysfunction.

References (1)
  1. (2023) "Product Information. Skyclarys (omaveloxolone)." Reata Pharmaceuticals, Inc.

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Skyclarys drug interactions

There are 460 drug interactions with Skyclarys (omaveloxolone).

Skyclarys alcohol/food interactions

There is 1 alcohol/food interaction with Skyclarys (omaveloxolone).


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.