Ketoconazole / pyrithione zinc topical Disease Interactions
There is 1 disease interaction with ketoconazole / pyrithione zinc topical:
Ketoconazole topical (applies to ketoconazole/pyrithione zinc topical) asthma
Moderate Potential Hazard, Moderate plausibility.
Ketoconazole cream 2% contains sodium sulfite that may cause allergic type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. Sulfite sensitivity is seen more frequently in asthmatic patients than in nonasthmatic people, and caution should be exercised when used on these patients.
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Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|