Isavuconazonium Disease Interactions
There are 2 disease interactions with isavuconazonium:
Isavuconazonium (Includes isavuconazonium) ↔ short QT
Severe Potential Hazard, Moderate plausibility. Applies to: Short QT Syndrome
Isavuconazonium has shown to shorten the QTc interval in a concentration- related manner. The use of this drug is contraindicated in patients with familial short QT syndrome.
Isavuconazonium (Includes isavuconazonium) ↔ liver disease
Moderate Potential Hazard, Moderate plausibility. Applies to: Liver Disease
The use of isavuconazonium has been associated with hepatic adverse reactions. Liver function tests should be performed at the start of therapy and periodically in patients with preexisting hepatic abnormalities. Treatment should be withdrawn if persistent elevations or worsening of liver enzyme levels occur. Isavuconazonium has not been studies in patients with severe hepatic impairment (Child-Pugh Class C) and should be used in these patients only when the benefits outweigh the risk.
Isavuconazonium drug interactions
There are 539 drug interactions with isavuconazonium
More about isavuconazonium
- Isavuconazonium Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- En Español
- Drug class: azole antifungals
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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