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Influenza virus vaccine, inactivated Disease Interactions

There are 2 disease interactions with influenza virus vaccine, inactivated.

Major

Influenza vaccine (applies to influenza virus vaccine, inactivated) GBS

Major Potential Hazard, Moderate plausibility. Applicable conditions: Guillain-Barre Syndrome

The use of influenza vaccine has been associated with an elevated risk of Guillain-Barré syndrome (GBS). It is not recommended to administer this vaccine if GBS has occurred within 6 weeks following previous influenza vaccination. Care and close monitoring is recommended and consideration of the potential benefits and risks should be assessed.

References (2)
  1. (2024) "Product Information. FluMist 2024-2025 (influenza virus vaccine, live)." Medimmune Inc
  2. (2025) "Product Information. Fluzone High-Dose (influenza virus vaccine, inactivated)." sanofi pasteur
Moderate

Vaccines (inactivated)/toxoids (applies to influenza virus vaccine, inactivated) immunodeficiency

Moderate Potential Hazard, High plausibility.

The expected serum antibody responses may not be obtained when vaccines and/or toxoids are administered to patients with primary or acquired immunodeficiency, including those with severe combined immunodeficiency, hypogammaglobulinemia or agammaglobulinemia, HIV infection, altered immune states (due to diseases such as leukemia, lymphoma, or generalized malignancy), or immunosuppression due to drug or other treatments (e.g., corticosteroids, alkylating agents, antimetabolites, or radiation).

References (14)
  1. (2001) "Product Information. Tetanus Toxoid Adsorbed (tetanus vaccine)." Aventis Pharmaceuticals
  2. (2022) "Product Information. Typhim VI (typhoid vaccine, inactivated)." Apothecon Inc
  3. (2022) "Product Information. Pneumovax 23 (pneumococcal 23-polyvalent vaccine)." Merck & Co., Inc
  4. "Product Information. Omnihib (haemophilus b conjugate vaccine (obsolete))." SmithKline Beecham
  5. "Product Information. Menomune A/C/Y/W-135 (meningococcal polysaccharide vaccine)." Connaught Laboratories Inc
  6. (2001) "Product Information. Plague Vaccine (plague vaccine)." Greer Laboratories Inc
  7. "Product Information. Havrix (HepA) (hepatitis A adult vaccine)." SmithKline Beecham
  8. (2022) "Product Information. Engerix-B (HepB) (hepatitis B adult vaccine)." Apothecon Inc
  9. (2006) "Product Information. Gardasil (human papillomavirus vaccine)." Merck & Co., Inc
  10. (2009) "Product Information. Cervarix (human papillomavirus vaccine)." GlaxoSmithKline
  11. (2022) "Product Information. Prevnar 13 (pneumococcal 13-valent conjugate vaccine)." Apothecon Inc
  12. (2016) "Product Information. Gardasil 9 (human papillomavirus vaccine)." Merck & Co., Inc
  13. (2025) "Product Information. Vimkunya Prefilled Syringe (cvx 329) (chikungunya vaccine, recombinant (cvx 329))." Bavarian Nordic, Inc.
  14. (2025) "Product Information. Fluzone High-Dose (influenza virus vaccine, inactivated)." sanofi pasteur

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Influenza virus vaccine, inactivated drug interactions

There are 311 drug interactions with influenza virus vaccine, inactivated.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.