Immune globulin intravenous Disease Interactions
There are 3 disease interactions with immune globulin intravenous.
Immune globulin intravenous (applies to immune globulin intravenous) HFI
Major Potential Hazard, Moderate plausibility. Applicable conditions: Fructose Intolerance
The immune globulin intravenous (human) injection, Flebogamma 10% DIF and Gammaplex contain sorbitol and should not be administered to patients with hereditary fructose intolerance (HFI).
Immune globulin intravenous (applies to immune globulin intravenous) renal disease
Major Potential Hazard, Moderate plausibility. Applicable conditions: Diabetes Mellitus, Renal Dysfunction, Sepsis
Renal abnormalities such as acute tubular necrosis, proximal tubular nephropathy, osmotic nephrosis, including acute renal dysfunction/failure and death have been reported after immune globulin intravenous (IGIV) products. Cases of renal dysfunction and acute renal failure occur more commonly in patients receiving IGIV products containing sucrose as a stabilizer. Ensure that patients are not volume-depleted before administering these agents and assess renal function, including measurement of blood urea nitrogen (BUN) and serum creatinine, before initiating the infusion and at appropriate intervals thereafter. If renal function deteriorates, consider discontinuation of the product. Periodic monitoring of renal function and urine output is important in patients at increased risk of developing acute renal failure. Administer these agents at the minimum dose and rate of infusion practicable in patients at risk for renal dysfunction or failure.
Immune globulin IV/SQ/IM (applies to immune globulin intravenous) thrombosis
Major Potential Hazard, Moderate plausibility. Applicable conditions: Diabetes Mellitus, Cardiovascular Disease, History - Thrombotic/Thromboembolic Disorder, Polycythemia, Hyponatremia
Thrombosis has been reported after treatment with immune globulin products. In general, patients at greatest risk of thromboembolic events are those of advanced age, prolonged immobilization, hypercoagulable conditions, history of venous or arterial thrombosis, use of estrogens, indwelling central vascular catheters, hyperviscosity, and cardiovascular risk factors. Thrombosis may occur in the absence of known risk factors; therefore, it is recommended that patients treated with these agents should be monitored for signs and symptoms of thrombosis and assess blood viscosity in patients at risk. Consider baseline assessment of blood viscosity in patients at risk for hyperviscosity.
Switch to professional interaction data
Immune globulin intravenous drug interactions
There are 105 drug interactions with immune globulin intravenous.
More about immune globulin intravenous
- immune globulin intravenous consumer information
- Check interactions
- Compare alternatives
- Reviews (27)
- Latest FDA alerts (1)
- Side effects
- Dosage information
- During pregnancy
- Drug class: immune globulins
- En español
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
See also:
Jaypirca
Jaypirca (pirtobrutinib) is a cancer medicine used to treat types of CLL, SLL, and MCL. Includes ...
Nplate
Nplate is used to prevent bleeding episodes in people with chronic immune thrombocytopenic purpura ...
Imbruvica
Imbruvica (ibrutinib) is used to treat chronic lymphocytic leukemia (CLL), small lymphocytic ...
Plaquenil
Plaquenil is used to treat or prevent malaria and to treat the symptoms of rheumatoid arthritis ...
Azathioprine
Azathioprine systemic is used for atopic dermatitis, autoimmune hepatitis, behcet's disease ...
Triamcinolone
Triamcinolone is used to treat allergies, skin conditions, ulcerative colitis, and arthritis. Learn ...
Hydroxychloroquine
Hydroxychloroquine is a quinoline drug used to treat or prevent malaria. It's also used to treat ...
Dexamethasone
Dexamethasone is used to treat inflammatory conditions such as allergies, skin conditions ...
Methotrexate
Methotrexate is used to treat certain types of cancer of the breast, skin, head and neck, or lung ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.