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Idarucizumab Disease Interactions

There are 2 disease interactions with idarucizumab:


Idarucizumab (Includes Idarucizumab) ↔ Fructose Intolerance

Moderate Potential Hazard, Moderate plausibility

Applies to: Fructose Intolerance

The recommended dose of idarucizumab contains 4 g of sorbitol. Caution is advised when prescribing this agent to patients with hereditary fructose intolerance. Consider the combined daily metabolic load of sorbitol/fructose from all sources to avoid serious adverse reactions.


Idarucizumab (Includes Idarucizumab) ↔ Liver Impairment

Moderate Potential Hazard, Moderate plausibility

Applies to: Liver Disease

No formal studies of idarucizumab have been conducted in patients with hepatic impairment. Caution is advised.

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

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