Idarucizumab Disease Interactions
There are 2 disease interactions with idarucizumab.
Idarucizumab (applies to idarucizumab) fructose intolerance
Moderate Potential Hazard, Moderate plausibility.
The recommended dose of idarucizumab contains 4 g of sorbitol. Caution is advised when prescribing this agent to patients with hereditary fructose intolerance. Consider the combined daily metabolic load of sorbitol/fructose from all sources to avoid serious adverse reactions.
Idarucizumab (applies to idarucizumab) liver impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
No formal studies of idarucizumab have been conducted in patients with hepatic impairment. Caution is advised.
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Idarucizumab drug interactions
There are 6 drug interactions with idarucizumab.
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- Drug class: anticoagulant reversal agents
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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