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Idarucizumab Dosage

Medically reviewed by Last updated on Dec 18, 2023.

Applies to the following strengths: 2.5 g/50 mL

Usual Adult Dose for Reversal of Anticoagulation

5 g IV provided as two separate vials each containing 2.5 g/50 mL; administer as a bolus injection by injecting both vials consecutively one after another via syringe or as two consecutive infusions.


Use: Reversal of the anticoagulant effects of dabigatran in patients requiring emergency surgery/urgent procedures or in the event of life-threatening or uncontrolled bleeding. This indication is approved under accelerated approval. Continued approval may be contingent upon the results of an ongoing cohort case series study.

Renal Dose Adjustments

No adjustment recommended

Liver Dose Adjustments

Data not available


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:

Storage requirements:

IV compatibility:


Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.