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Addyi (flibanserin) Disease Interactions

There are 3 disease interactions with Addyi (flibanserin):


Flibanserin (Includes Addyi) ↔ Acute Alcohol Intoxication

Severe Potential Hazard, Moderate plausibility

Applies to: Alcoholism

The use of flibanserin is contraindicated along with the ingestion of alcohol, as it increases the risk of hypotension and syncope. It is important to assess the likelihood of the patient abstaining from alcohol, taking into account the current and past drinking behavior.


Flibanserin (Includes Addyi) ↔ Hypotension/Syncope

Severe Potential Hazard, Moderate plausibility

Applies to: Hypotension, Syncope

The use of flibanserin can cause hypotension and syncope. The benefits and risks of therapy should be considered in patients with preexisting conditions that predispose to hypotension. Flibanserin should be used with caution in these patients.


Flibanserin (Includes Addyi) ↔ Liver Disease

Severe Potential Hazard, Moderate plausibility

Applies to: Liver Disease

Flibanserin may accumulate in patients with hepatic impairment. Therapy with flibanserin is contraindicated in patients with compromised hepatic function.

Addyi (flibanserin) drug Interactions

There are 846 drug interactions with Addyi (flibanserin)

Addyi (flibanserin) alcohol/food Interactions

There is 1 alcohol/food interaction with Addyi (flibanserin)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

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