Addyi Side Effects
Generic Name: flibanserin
Note: This document contains side effect information about flibanserin. Some of the dosage forms listed on this page may not apply to the brand name Addyi.
Common side effects of Addyi include: syncope, central nervous system depression, dizziness, drowsiness, fatigue, nausea, sedation, and hypotension. Other side effects include: insomnia. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to flibanserin: oral tablet
Along with its needed effects, flibanserin (the active ingredient contained in Addyi) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking flibanserin:More common
- Blurred vision
- dizziness, fainting, or lightheadedness, especially when getting up suddenly from a lying or sitting position
- unusual tiredness or weakness
- sleepiness or unusual drowsiness
- Feeling of constant movement of self or surroundings
- sensation of spinning
- severe cramping
- stomach or lower abdominal pain
Some side effects of flibanserin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less common
- dry mouth
- normal menstrual bleeding occurring earlier, possibly lasting longer than expected
- trouble sleeping
For Healthcare Professionals
Applies to flibanserin: oral tablet
When this drug is used alone, the incidence of hypotension is 0.2% and syncope is 0.4%. When this drug is taken with 0.4 g/kg alcohol, 17% had substantial reductions in blood pressure, resulting in hypotension and/or syncope requiring medical intervention. When 0.8 g/kg alcohol was taken in combination with this drug, 25% experienced orthostatic hypotension.[Ref]
Uncommon (0.1% to 1%): Hypotension, syncope[Ref]
Very common (10% or more): Dizziness (11.4%), somnolence (11.2%)
Common (1% to 10%): Sedation, fatigue, vertigo[Ref]
Patients taking hormonal contraceptives (HC) had a greater incidence of dizziness, somnolence, and fatigue compared to patients who did not use HC.[Ref]
-Serious adverse reactions were reported in 0.9% of patients. The discontinuation rate due to adverse reactions was 13%. The most common adverse reactions leading to discontinuation were dizziness, nausea, insomnia, somnolence, and anxiety.
-The majority of adverse reactions began within the first 14 days of treatment.[Ref]
Common (1% to 10%): Accidental injury[Ref]
Among patients who experienced accidental injury, 21% reported adverse reactions consistent with CNS depression (e.g., somnolence, sedation, or fatigue) within the preceding 24 hours.[Ref]
Common (1% to 10%): Insomnia, anxiety[Ref]
Very common (10% or more): Nausea (10.4%)
Common (1% to 10%): Dry mouth, constipation
Uncommon (0.1% to 1%): Appendicitis[Ref]
Common (1% to 10%): Metrorrhagia[Ref]
Common (1% to 10%): Abdominal pain[Ref]
Common (1% to 10%): Rash[Ref]
1. "Product Information. Addyi (flibanserin)." Sprout Pharmaceuticals, Raleigh, NC.
Some side effects of Addyi may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
More about Addyi (flibanserin)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 4 Reviews – Add your own review/rating
- Drug class: miscellaneous central nervous system agents
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