Tensilon Disease Interactions
There are 3 disease interactions with Tensilon (edrophonium).
Cholinesterase inhibitor (applies to Tensilon) coronary artery disease
Major Potential Hazard, High plausibility. Applicable conditions: Ischemic Heart Disease
The use of cholinesterase inhibitors has been associated with a constriction of coronary arteries. Therapy with cholinesterase inhibitors should be administered cautiously in patients with coronary artery disease.
References (8)
- (2001) "Product Information. Cognex (tacrine)." Parke-Davis
- Benjamin KW (1979) "Toxicity of ocular medications." Int Ophthalmol Clin, 19, p. 199-255
- "Product Information. Phospholine Iodide (echothiophate iodide ophthalmic)." Wyeth-Ayerst Laboratories
- (2001) "Product Information. Mestinon (pyridostigmine)." ICN Pharmaceuticals Inc
- "Product Information. Prostigman (neostigmine)." ICN Pharmaceuticals Inc, Cost Mesa, CA.
- (2001) "Product Information. Aricept (donepezil)." Pfizer U.S. Pharmaceuticals
- "Product Information. Humorsol Ocumeter (demecarium bromide ophthalmic)." Merck & Co., Inc
- "Product Information. Eserine Sulfate Ophthalmic (PHYSostigmine ophthalmic)." Ciba Vision Ophthalmics
Cholinesterase inhibitor (applies to Tensilon) parkinsonism
Major Potential Hazard, High plausibility.
Cholinesterase inhibitors should be used with caution in patients with parkinsonism. Some of these drugs might be contraindicated in these patients (refer to specific prescribing information). Symptoms of Parkinson's disease may be exacerbated with the increase in cholinergic activity. Caregivers and patients should be advised.
References (8)
- (2001) "Product Information. Cognex (tacrine)." Parke-Davis
- el-Yousef MK, Janowsky D, Davis JM, Sekerke HJ (1973) "Reversal of antiparkinsonian drug toxicity by physostigmine: a controlled study." Am J Psychiatry, 130, p. 141-5
- Benjamin KW (1979) "Toxicity of ocular medications." Int Ophthalmol Clin, 19, p. 199-255
- "Product Information. Phospholine Iodide (echothiophate iodide ophthalmic)." Wyeth-Ayerst Laboratories
- (2001) "Product Information. Aricept (donepezil)." Pfizer U.S. Pharmaceuticals
- "Product Information. Humorsol Ocumeter (demecarium bromide ophthalmic)." Merck & Co., Inc
- "Product Information. Eserine Sulfate Ophthalmic (PHYSostigmine ophthalmic)." Ciba Vision Ophthalmics
- (2001) "Product Information. Exelon (rivastigmine)." Novartis Pharmaceuticals
Cholinesterase inhibitor (applies to Tensilon) hyperthyroidism
Moderate Potential Hazard, High plausibility.
Many of the manifestations of hyperthyroidism may be exacerbated by increased levels of acetylcholine produced by cholinesterase inhibitors. Therapy with cholinesterase inhibitors should be administered cautiously to patients with hyperthyroidism. Monitoring of thyroid levels is recommended.
References (5)
- (2001) "Product Information. Cognex (tacrine)." Parke-Davis
- Benjamin KW (1979) "Toxicity of ocular medications." Int Ophthalmol Clin, 19, p. 199-255
- (2001) "Product Information. Mestinon (pyridostigmine)." ICN Pharmaceuticals Inc
- "Product Information. Prostigman (neostigmine)." ICN Pharmaceuticals Inc, Cost Mesa, CA.
- (2001) "Product Information. Aricept (donepezil)." Pfizer U.S. Pharmaceuticals
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Tensilon drug interactions
There are 90 drug interactions with Tensilon (edrophonium).
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- Drug class: cholinergic muscle stimulants
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Regonol
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Prostigmin Bromide
Prostigmin Bromide is used for myasthenia gravis, urinary retention
Sugammadex
Sugammadex systemic is used for reversal of neuromuscular blockade, reversal of nondepolarizing ...
Neostigmine
Neostigmine systemic is used for myasthenia gravis, reversal of neuromuscular blockade, reversal of ...
Pyridostigmine
Pyridostigmine systemic is used for dysautonomia, myasthenia gravis, nerve agent pretreatment ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.