Gentran 70 Disease Interactions
There are 4 disease interactions with Gentran 70 (dextran, high molecular weight).
Dextran (applies to Gentran 70) cardiac failure
Major Potential Hazard, Moderate plausibility. Applicable conditions: Heart Disease
Low molecular weight and high molecular weight dextran is contraindicated in patients with marked cardiac decompensation.
Dextran (applies to Gentran 70) hemostatic defects
Major Potential Hazard, Moderate plausibility. Applicable conditions: Bleeding Associated with Coagulation Defect, Thrombocytopenia
The use of dextran is contraindicated in patients with marked hemostatic defects of all types (thrombocytopenia, hypofibrinogenemia, etc.) including those caused by drugs such as heparin, warfarin, etc.
Dextran (applies to Gentran 70) renal impairment
Major Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
Low molecular and high molecular weight dextran are contraindicated in patients with renal disease with severe oliguria or anuria.
Dextran (applies to Gentran 70) bleeding
Moderate Potential Hazard, Moderate plausibility.
Caution should be employed when using dextran (low and high molecular weight) in patients with active hemorrhage as the resulting increase in perfusion pressure and improved microcirculatory flow may result in additional blood loss.
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Gentran 70 drug interactions
There are 32 drug interactions with Gentran 70 (dextran, high molecular weight).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.