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Collagenase clostridium histolyticum Disease Interactions

There is 1 disease interaction with collagenase clostridium histolyticum.

Major

Collagenase clostridium histolyticum (applies to collagenase clostridium histolyticum) coagulation disorders

Major Potential Hazard, Moderate plausibility. Applicable conditions: Coagulation Defect

Collagenase clostridium histolyticum for injection should be avoided in patients with coagulation disorders, including those receiving concomitant anticoagulant medications, other than low-dose aspirin within seven days prior to therapy administration. Care should be exercised if collagenase clostridium histolyticum for injection is used in these patients.

References

  1. "Product Information. Xiaflex (collagenase clostridium histolyticum)." Auxilium Pharmaceuticals Inc (2010):

Collagenase clostridium histolyticum drug interactions

There are 55 drug interactions with collagenase clostridium histolyticum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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