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E-Z-Gas II (citric acid / simethicone / sodium bicarbonate) Disease Interactions

There is 1 disease interaction with E-Z-Gas II (citric acid / simethicone / sodium bicarbonate):


Alkalinizing agents (Includes E-Z-Gas II) ↔ sodium/water balance

Severe Potential Hazard, High plausibility. Applies to: Congestive Heart Failure, Fluid Retention, Hypernatremia

Alkalinizing agents containing sodium can induce sodium and water retention and result in hypernatremia, hypokalemia, hyperosmolality, edema and aggravation of congestive heart failure. Therapy with sodium- containing alkalinizing agents should not be used in patients with hypernatremia or fluid retention. Clinical monitoring of acid/base balance and electrolytes prior to, during, a following completion of therapy with alkalinizing agents is recommended.


  1. "Product Information. Sodium Bicarbonate (sodium bicarbonate)." Astra USA, Westborough, MA.
  2. "Product Information. Sodium Lactate (sodium lactate)." Abbott Pharmaceutical, Abbott Park, IL.

E-Z-Gas II (citric acid / simethicone / sodium bicarbonate) drug interactions

There are 397 drug interactions with E-Z-Gas II (citric acid / simethicone / sodium bicarbonate)

More about E-Z-Gas II (citric acid / simethicone / sodium bicarbonate)

Related treatment guides

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.