Carglumic acid Disease Interactions
There is 1 disease interaction with carglumic acid.
Carglumic acid (applies to carglumic acid) renal impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
Plasma concentrations of carglumic acid are increased in patients with renal impairment. Dose reductions are recommended in patients with moderate or severe renal impairment. The pharmacokinetics of carglumic acid in patients with ESRD have not been evaluated.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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