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Carglumic Acid Dosage

Medically reviewed by Drugs.com. Last updated on Apr 4, 2024.

Applies to the following strengths: 200 mg

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Hyperammonemia

For the Treatment of Acute or Chronic Hyperammonemia due to NAGS (N-acetylglutamate synthase) Deficiency:

Comments:

For the Treatment of Acute Hyperammonemia due to PA (Propionic Acidemia) or MMA (Methylmalonic Acidemia):
Comments:

Comments:

Uses:

Usual Pediatric Dose for Hyperammonemia

For the Treatment of Acute or Chronic Hyperammonemia due to NAGS (N-acetylglutamate synthase) Deficiency:

Comments:

For the Treatment of Acute Hyperammonemia due to PA (Propionic Acidemia) or MMA (Methylmalonic Acidemia):
Comments:

Comments:

Uses:

Renal Dose Adjustments

Mild renal impairment (eGFR 60 mL/min/1.73 m2 or greater): No adjustment recommended
Moderate renal impairment (eGFR 30 to 59 mL/min/1.73 m2):

Severe renal impairment (eGFR 29 mL/min/1.73 m2 or less):

Liver Dose Adjustments

Data not available

Dose Adjustments

Therapeutic Monitoring For NAGS Deficiency:

Precautions

CONTRAINDICATIONS: None

Safety and efficacy have not been established in geriatric population.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


Oral Administration:

Nasogastric (NG) Tube Administration:

Oral Syringe Administration:

Storage requirements:
Before use: Store in original container in the refrigerator 36F to 46F (2C to 8C)
After opening container: Store at room temperature; do not refrigerate

General:

Monitoring:

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.