Fasenra Disease Interactions
There is 1 disease interaction with Fasenra (benralizumab).
Benralizumab (applies to Fasenra) infections
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral
Anti-benralizumab antibodies were associated with increased clearance of benralizumab and increased blood eosinophil levels in patients with high anti-drug antibody titers compared to antibody negative patients. Eosinophils may be involved in the immunological response to some helminth infections. It is recommended to treat patients with preexisting helminth infections before starting therapy with benralizumab. Treatment should be discontinued if patients become infected while on treatment, and do not respond to helminth treatment. Treatment may be restarted once infection resolves.
- "Product Information. Fasenra (benralizumab)." Astra-Zeneca Pharmaceuticals (2017):
Fasenra drug interactions
There are 2 drug interactions with Fasenra (benralizumab).
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Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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