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Eraxis (anidulafungin) Disease Interactions

There is 1 disease interaction with Eraxis (anidulafungin):

Moderate

Echinocandins (Includes Eraxis) ↔ Hepatotoxicity

Moderate Potential Hazard, Moderate plausibility

Applies to: Liver Disease

Laboratory abnormalities in liver function tests have been observed in healthy volunteers and patients treated with echinocandins, and clinical hepatic abnormalities have occurred in some patients with serious underlying conditions who were receiving multiple concomitant medications with echinocandin therapy. Isolated cases of significant hepatic dysfunction, hepatitis, or worsening hepatic failure have also been reported, although a causal relationship has not been established. Therapy with echinocandins should be administered cautiously in patients with preexisting liver disease. Liver function should be monitored regularly during therapy.

References

  1. "Product Information. Mycamine (micafungin)." Fujisawa, Deerfield, IL.
  2. "Product Information. Eraxis (anidulafungin)." Pfizer U.S. Pharmaceuticals Group, New York, NY.
  3. "Product Information. Cancidas (caspofungin)" Merck & Co, Inc, West Point, PA.

Eraxis (anidulafungin) drug Interactions

There is 1 drug interaction with Eraxis (anidulafungin)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.

Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.

Do not stop taking any medications without consulting your healthcare provider.

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