Trientine Alternatives Compared
| Trientine | Penicillamine | Cuprimine (penicillamine) |
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| Trientine | Penicillamine | Cuprimine (penicillamine) |
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Prescription only
Prescribed for Wilson's Disease. Trientine may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Wilson's Disease, Cystinuria, Rheumatoid Arthritis. Penicillamine may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Wilson's Disease, Cystinuria, Rheumatoid Arthritis. Cuprimine may also be used for purposes not listed in this medication guide. |
Related suggestions Wilson's Disease
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| More about Trientine | More about Penicillamine | More about Cuprimine (penicillamine) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Trientine has an average rating of 10.0 out of 10 from a total of 1 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Penicillamine has an average rating of 9.0 out of 10 from a total of 2 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Cuprimine has an average rating of 10.0 out of 10 from a total of 1 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
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View all Trientine side effects |
View all Penicillamine side effects |
View all Cuprimine side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Trientine prices |
View all Penicillamine prices |
View all Cuprimine prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Clovique, Cuvrior, Syprine | Cuprimine, D-Penamine, Depen, Depen Titratabs | Other penicillamine brands include: D-Penamine, Depen, Depen Titratabs | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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N/A |
3.2 hours |
3.2 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 46 drugs are known to interact with Trientine:
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A total of 123 drugs are known to interact with Penicillamine:
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A total of 123 drugs are known to interact with Cuprimine:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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November 08, 1985 |
December 04, 1970 |
December 04, 1970 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient Resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.