Comparing Spironolactone vs Hydrochlorothiazide / Triamterene
Spironolactone | Hydrochlorothiazide / triamterene |
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Spironolactone | Hydrochlorothiazide / triamterene |
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Prescription only
Spironolactone is a diuretic that may be used to remove excess fluid (edema) from the body, lower blood pressure, or treat hyperaldosteronism. It does not cause potassium loss from the body; however... View more |
Prescription only
Prescribed for Edema, High Blood Pressure. hydrochlorothiazide / triamterene may also be used for purposes not listed in this medication guide. |
Related suggestions High Blood Pressure (Hypertension)
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More about Spironolactone | More about Hydrochlorothiazide / triamterene | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Spironolactone has an average rating of 6.9 out of 10 from a total of 694 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 25% reported a negative effect. |
Hydrochlorothiazide / triamterene has an average rating of 5.8 out of 10 from a total of 69 ratings on Drugs.com. 42% of reviewers reported a positive effect, while 33% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: spironolactone side effects in more detail. |
See also: hydrochlorothiazide / triamterene side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all spironolactone prices |
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Dosage Form(s) Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Aldactone, CaroSpir | Dyazide, Maxzide, Maxzide-25 | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
37 hours |
12 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 382 drugs are known to interact with spironolactone:
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A total of 512 drugs are known to interact with hydrochlorothiazide / triamterene:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
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First Approval Date | |||||||||||||||||
January 21, 1960 |
December 02, 1965 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.