Comparing Spironolactone vs Digoxin
Spironolactone | Digoxin |
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Spironolactone | Digoxin |
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Prescription only
Spironolactone is a diuretic that may be used to remove excess fluid (edema) from the body, lower blood pressure, or treat hyperaldosteronism. It does not cause potassium loss from the body; however... View more |
Prescription only
Digoxin is one of the oldest and most controversial heart medications. In heart failure, it is usually only used alongside standard medications. In atrial fibrillation, there is still much debate... View more |
Related suggestions Heart Failure (Congestive Heart Failure)
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More about Spironolactone | More about Digoxin | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Spironolactone has an average rating of 6.9 out of 10 from a total of 694 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 25% reported a negative effect. |
Digoxin has an average rating of 5.8 out of 10 from a total of 17 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 35% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: spironolactone side effects in more detail. |
See also: digoxin side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all spironolactone prices |
View all digoxin prices |
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Dosage Form(s) Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Aldactone, CaroSpir | Cardoxin, Digitek, Digox, Lanoxin | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
37 hours |
144 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 382 drugs are known to interact with spironolactone:
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A total of 428 drugs are known to interact with digoxin:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
January 21, 1960 |
July 26, 1982 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.