Propylthiouracil Alternatives Compared
| Propylthiouracil | Methimazole | Tapazole |
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| Propylthiouracil | Methimazole | Tapazole (methimazole) |
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Prescription only
Prescribed for Hyperthyroidism, Thyroid Storm, Alcoholic Liver Damage. propylthiouracil may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Hyperthyroidism. methimazole may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Hyperthyroidism. Tapazole may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Propylthiouracil | More about Methimazole | More about Tapazole (methimazole) | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Propylthiouracil has an average rating of 10.0 out of 10 from a total of 4 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Methimazole has an average rating of 5.5 out of 10 from a total of 110 ratings on Drugs.com. 36% of reviewers reported a positive effect, while 33% reported a negative effect. |
Tapazole has an average rating of 8.8 out of 10 from a total of 4 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Drug Class | ||||||||||||||||||
| Side Effects | ||||||||||||||||||
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See also: propylthiouracil side effects in more detail. |
See also: methimazole side effects in more detail. |
See also: Tapazole side effects in more detail. |
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| Generic Availability | ||||||||||||||||||
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Lower cost generic |
Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
View all propylthiouracil prices |
View all methimazole prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms Available | ||||||||||||||||||
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| Brand Names | ||||||||||||||||||
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N/A |
Tapazole |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
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5 hours |
13 hours |
13 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 65 drugs are known to interact with propylthiouracil:
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A total of 62 drugs are known to interact with methimazole:
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A total of 62 drugs are known to interact with Tapazole:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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July 28, 1947 |
June 21, 1950 |
June 21, 1950 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.