Comparing Promethazine vs Zyrtec
Promethazine | Zyrtec |
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Promethazine | Zyrtec (cetirizine) |
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Prescription only
Promethazine may be used to relieve allergy symptoms and nausea. Sedation is the main side effect and it may interact with several other drugs including antidepressants, antipsychotics, and other... View more |
Prescription and OTC
Zyrtec is an antihistamine that effectively treats allergic reactions such as hay fever or skin reactions caused by insect bites. Although drowsiness with Zyrtec is uncommon, Zyrtec is more likely... View more |
Related suggestions Allergic Rhinitis
Urticaria
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More about Promethazine | More about Zyrtec (cetirizine) | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Promethazine has an average rating of 7.3 out of 10 from a total of 380 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 21% reported a negative effect. |
Zyrtec has an average rating of 5.8 out of 10 from a total of 197 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 35% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: promethazine side effects in more detail. |
See also: Zyrtec side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic approved | ||||||||||||||||
Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all promethazine prices |
View all Zyrtec prices |
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Dosage Form(s) Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Adgan, Anergan 50, Antinaus 50, Phenadoz, Promethegan | Other cetirizine brands include: All Day Allergy, All Day Allergy Children's, Aller-Tec, Aller-Tec Children's, Alleroff, Children's Allergy Relief, Equate Allergy Relief, PediaCare Children's 24-Hour Allergy, Quzyttir, Zyrtec Hives View more | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
16 hours |
10.6 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 685 drugs are known to interact with promethazine:
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A total of 256 drugs are known to interact with Zyrtec:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
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First Approval Date | |||||||||||||||||
March 29, 1951 |
N/A |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.