Comparing Afinitor vs Nexavar
| Afinitor Remove Afinitor from your drug comparison | Nexavar Remove Nexavar from your drug comparison |
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| Afinitor everolimus Remove Afinitor from your drug comparison | Nexavar sorafenib Remove Nexavar from your drug comparison | ||||||||||||||||
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Afinitor (everolimus) is a targeted medicine that may be used to treat various cancers and TSC-associated conditions. It reduces the blood supply to the cancers which slows down their growth and... View more |
Prescribed for Hepatocellular Carcinoma, Hepatic Tumor, Renal Cell Carcinoma, Thyroid Cancer. Nexavar may also be used for purposes not listed in this medication guide. |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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5.6
For Breast Cancer: Although the medication did effectively treat my cancer the side effects were so severe that I decided to discontinue use of the drug and try an alternate treatment. Skin rash started on my hands initially and spread to my entire body causing severe itching and scratching which led to something looking like opened bug bites all over. Severe gum irritation described by my dental hygienist as your gums are flapping in the wind, also red swollen gums which caused me to be unable to eat anything not soft. Lost 10 lbs the first two months. Also projectile vomiting, diahrea and nausea. At three months I found it had made me diabetic and raised my triglycerides to over 500. That's when I opted to stop treatment. |
5.4
For Hepatocellular Carcinoma: I've been on this medication now for 11 days and on the 10th day I got a bad rash on my whole body from neck to toe. I've stopped the medication and will continue when the rash goes away. I also have had my blood pressure raise quite a bit. I don't really like the way the medicine makes me feel but if it will give me a few more years on this earth I guess I can make a go of it! For Hepatocellular Carcinoma: I have been taking Nexavar since May 5/12. I have tenderness in my hands and feet and dry skin. Energy level is good. |
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Drug Class |
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Side Effects |
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Common side effects include: infection, decreased hemoglobin, increased serum glucose, lymphocytopenia, and stomatitis. See the full Afinitor side effects document. |
Common side effects include: alopecia, arthralgia, desquamation, diarrhea, exfoliation of skin, fatigue, headache, hemorrhage, hypertension, hypophosphatemia, increased serum lipase, lymphocytopenia, neutropenia, palmar-plantar erythrodysesthesia, peripheral sensory neuropathy, pruritus, skin rash, weight loss, increased amylase, and xeroderma. See the full Nexavar side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all Afinitor prices and generic prices |
View all Nexavar prices |
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Generic Availability |
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No |
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Dosage Form(s) Available |
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Brand Names |
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| Other everolimus brands include: Afinitor Disperz, Zortress |
N/A |
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Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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35 hours |
48 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
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FDA Alerts |
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N/A |
N/A |
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Drug Interactions |
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A total of 415 drugs are known to interact with Afinitor:
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A total of 367 drugs are known to interact with Nexavar:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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March 30, 2009 |
December 01, 2005 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Breast Cancer: I have been taking Afinitor for about 2 weeks. Just feel I cannot continue in with it, feeling like my heart is racing for hours after taking it, it feels close to a panic feeling. No mouth sores(yet) doing the steroid mouth swish as ordered. However, I suddenly have a cluster of large pimple like sores on inner thighs, my skin in general feels very dry. I just cannot deal with sores and am terrified they will become wide spread. I was on Ibrance a year and then it stopped working. The only side effect was fatigue, that I can deal with but sores - no. calling my doctor and telling him the side effects are too much! Give me a med that has fewer serious side effects! I have not taken it long enough to evaluate if it is even being effective. Just no the side effects have begun right away.